Publications by authors named "Piyapasara Toapichattrakul"
Changing of gamma-H2AX in peripheral blood mononuclear cells during concurrent chemoradiation in locally advanced rectal cancer patients: a potential response predictor.
J Gastrointest Oncol
October 2024
Background: The most detrimental effect of DNA damage from radiation is DNA double-strand breaks, making it critical to identify reliable biomarkers for treatment response in cancer therapy. Gamma-H2AX (γ-H2AX), a marker of DNA double-strand breaks, was evaluated in this study as a potential biomarker for treatment response in locally advanced rectal cancer patients undergoing preoperative concurrent chemoradiation (CCRT).
Methods: Thirty patients with locally advanced rectal cancer received preoperative CCRT.
Objective: This retrospective study evaluated the preliminary outcomes of image-guided vaginal brachytherapy (IG-VBT) in the adjuvant treatment of high intermediate risk endometrial cancer.
Materials And Methods: Data were collected from 48 patients who underwent adjuvant IG-VBT between 2019 and 2022 at the Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University. The vaginal cuff clinical target volume (CTV-VC) is composed of a 4-mm-thick band around vaginal cylinder at the upper 3 cm of the vaginal cuff.
Article Synopsis
- Radiation-induced brachial plexopathy (RIBP) is a concerning side effect after hypofractionated postmastectomy radiotherapy (HF-PMRT) in breast cancer patients, and this study aimed to investigate its occurrence and dosimetric parameters using intensity-modulated radiation therapy (IMRT).
- The study involved 229 breast cancer patients, with assessments of RIBP symptoms using a questionnaire and comprehensive physical evaluations, revealing that most patients had normal function and no severe RIBP events occurred.
- Dosimetric analysis showed similar radiation dose parameters among patients, and the findings suggest that using HF-PMRT by helical tomotherapy is a safe approach for treating the chest wall in breast cancer cases.