Climate change and coastal morphodynamics: Interactions on regional scales.

Climate change and its impacts, combined with unchecked human activities, intensify pressures on coastal environments, resulting in modification of the coastal morphodynamics. Coastal zones are intricate and constantly changing areas, making the monitoring and interpretation of data a challenging task, especially in remote beaches and regions with limited historical data. Traditionally, remote sensing and numerical methods have played a vital role in analysing earth observation data and supporting the monitoring and modelling of complex coastal ecosystems.

Interaction of climate change and marine pollution in Southern India: Implications for coastal zone management practices and policies.

Climate change and marine litter are inextricably linked, and their interaction manifests differently depending on the specific environmental and biological characteristics, and other human activities taking place. The negative impacts resulting from those synergistic interactions are threatening coastal and marine ecosystems and the many goods and services they provide. This is particularly pervasive in the coastal zone of the Indian subcontinent.

Estrogen receptors as potential therapeutic target in endometrial cancer.

Endometrial cancer (EC) is one of the most common gynecological carcinomas in both developed and developing countries. Majority of the gynecological malignancies are hormonally driven where estrogen signaling acts as an oncogenic signal. Estrogen's effects are mediated classical nuclear estrogen receptors; estrogen receptor alpha and beta (ERα and ERβ) and a trans-membrane G protein-coupled estrogen receptor (GPR30 and GPER).

Marine litter and climate change: Inextricably connected threats to the world's oceans.

The global issues of climate change and marine litter are interlinked and understanding these connections is key to managing their combined risks to marine biodiversity and ultimately society. For example, fossil fuel-based plastics cause direct emissions of greenhouse gases and therefore are an important contributing factor to climate change, while other impacts of plastics can manifest as alterations in key species and habitats in coastal and marine environments. Marine litter is acknowledged as a threat multiplier that acts with other stressors such as climate change to cause far greater damage than if they occurred in isolation.

Effects of bisphenol A (BPA) on brain-specific expression of cyp19a1b gene in swim-up fry of Labeo rohita.

Estrogen regulates numerous developmental and physiological processes and effects are mediated mainly by estrogenic receptors (ERs), which function as ligand-regulated transcription factor. ERs can be activated by many different types endocrine disrupting chemicals (EDCs) and interfere with behaviour and reproductive potential of living organism. Estrogenic regulation of membrane associated G protein-coupled estrogen receptor, GPER activity has also been reported.

Metabolism of 2-hydroxy-1-naphthoic acid and naphthalene via gentisic acid by distinctly different sets of enzymes in Burkholderia sp. strain BC1.

Burkholderia sp. strain BC1, a soil bacterium, isolated from a naphthalene balls manufacturing waste disposal site, is capable of utilizing 2-hydroxy-1-naphthoic acid (2H1NA) and naphthalene individually as the sole source of carbon and energy. To deduce the pathway for degradation of 2H1NA, metabolites isolated from resting cell culture were identified by a combination of chromatographic and spectrometric analyses.

Complete degradation of di-n-octyl phthalate by Gordonia sp. strain Dop5.

The present study describes the assimilation of di-n-octyl phthalate by an aerobic bacterium, isolated from municipal waste-contaminated soil sample utilizing di-n-octyl phthalate as the sole source of carbon and energy. The isolate was identified as Gordonia sp. based on the morphological, nutritional and biochemical characteristics as well as 16S rRNA gene sequence analysis.

The neuronal apoptotic death in global cerebral ischemia in gerbil: important role for sodium channel modulator.

Global ischemia was induced in gerbil by bilateral occlusion of the common carotid arteries for 5 min. Sodium ionophore monensin or sodium channel blocker tetrodotoxin (TTX) was administered at doses of 10 micorg/kg, i.p.

Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart.

Prevailing data suggest that sarcolemmal ATP-sensitive (K(ATP)) channels in the adult heart consist of Kir6.2 and SUR2A subunits, but the expression of other K(ATP) channel subunits (including SUR1, SUR2B, and Kir6.1) is poorly defined.