[The risk groups of infection with hepatitis С virus in conditionally healthy population of the Belgorod oblast].

The purpose of study was to establish risk group on hepatitis C in conditionally healthy population of the Belgorod oblast. Total 2025 conditionally healthy inhabitants aged between 1 and 99 were surveyed and serum samples from them were tested. There were eight age groups: 1-14 years (12.

[Behcet's disease with neurologic manifestations].

Behcet's disease (BD) is a type of systematic chronic inflammatory disease of unknown etiology that is characterized by the combination of recurrent oral aphthous, genital ulcers and uveitis. A damage of the nervous system is observed in 3-9% of patients, in which two variants of the course of the disease are possible: parenchymal in the form of immune-mediated meningoencephalitis, and non-parenchymal, which can be represented by venous sinus thrombosis, intracranial arterial aneurysms and intracranial hypertension. The article presents a clinical case of BD with a dominant nervous system damage in the clinical presentations of the disease.

The substantiation of the elastic-viscoplastic model of the human spine for modeling the correction process of kyphoscoliotic deformation.

Purpose: The relevance of the problem is caused by an increase in the number of spine-related diseases among children, including scoliosis. Currently, there are no methodologies for the treatment of scoliosis, which ensure an unambiguous positive result. The purpose of the article is to justify the spinal model as an elastic viscoplastic body for further mathematical modeling of the process of spine correction and search for its optimal conditions.

Mechanism of inhibiting effect of biologically active compounds on the active forms of oxygen reduction.

The impulse voltammetry methods with recording short-living radical-natured products of the reduction (in particular, hydroxyl radicals) are used to study the process of oxygen reduction steps. A possibility to study mechanisms of antioxidative action of biologically active compounds (BAC) through studying their influence on the separate steps of oxygen reduction (initial molecular oxygen, radical particles and peroxides) is shown. It provides a possibility for the purposeful search of BAC capable to affect certain steps of chain oxidation in biosystems.

[Carcinogenic N-nitrosamines in the tire industry].

The level of volatile carcinogenic N-nitrosamines (NA) was studied in the air of various technological sites of tyre production. Reported total levels of NA in air exceeded MACs set in certain countries for the same enterprises. For example, German total MAC for 12 carcinogenic NA is 1 g/m3.

[Enterosorption in the combined treatment of patients with viral hepatitis].

The authors studied the efficacy of using USSR-made adsorbent "Enterosgel" in the complex treatment of viral hepatitis. A scheme of employment of the drug is described. Recommendations on the doses and duration of treatment are given.

[Antinuclear, anticentromere and anti-ScL-70 antibodies in rheumatic diseases].

Methods are described that are used for the titration of antinuclear, anticentromere, and anti-Scl-70 antibodies in systemic scleroderma, systemic lupus erythematosus, and rheumatoid arthritis: indirect immunofluorescence with various antigenic substrates (sections of fresh-frozen rat liver and Hep-2 cell culture), counter-current immunoelectrophoresis, isolation of Scl-70 antigen. Use of Hep-2 cells as a substrate for indirect immunofluorescence was found clinically and diagnostically more effective since it permitted the detection of anticentromere antibodies and anti-Scl-70. Nucleolar, mottled, homogeneous, marginal immunofluorescence types were observed when rat liver sections and Hep-2 cells were used for substrates.

[Features of the functional status of the pancreas and liver after vagotomy].

A study of 578 patients with different kinds of postvagotomy disorders revealed disorders of the incretory and excretory pancreatic function as well as of the absorptive function of the polygonal liver cells. It was established that an increase of the concentration of immunoreactive insulin and C-peptide with simultaneous reduction of immunoreactive trypsin and accumulation of the radioactive agent in the liver may be used as a diagnostic test of incomplete vagotomy.

[Effect of diet on transport ATPase activity in myocardial and liver membranes].

Distinct impairments were found in membranes of rat myocardium and liver tissue in animals kept on food, which was deficient in retinol, tocopherol, ascorbic acid and essential amino acids lysine, methionine and threonine. Deficiency in these dietary components led to a decrease in content of phosphatidyl ethanolamine and phosphatidyl serine and in activity of total ATPase and Ca2+-ATPase in membranes of myocardial sarcoplasmic reticulum as well as to decrease Na+, K+-ATPase activity in liver plasmatic membrane.