Publications by authors named "Pitchiah Sivaperumal"

Recent advancements in cancer research focus on reducing treatment side effects while enhancing efficacy against medication resistance and tumor antigen detection. Genetic therapies utilizing microbes like bacteria, fungi, and viruses have garnered attention, with mycoviruses emerging as promising candidates. Particularly, the smallest fungal virus, Myco-phage, exhibits oncolytic properties by lysing cancer cells in the mouth, oral cavity, head, and neck without adverse effects.

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The development of self-preserving personal care cosmetics represents a significant advancement in the cosmetics industry, offering safer and more natural alternatives to consumers. This study focused on the preparation of such formulations using multifunctional ingredients along with other cosmetic components. Five unique multifunctional ingredients (MFIs) were identified based on their antimicrobial properties: sodium coco PG-dimonium chloride phosphate, ricinoleic acid, palmitoleic acid, raspberry ketone, and sorbitan caprylate.

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Efficient tissue regeneration following oral cancer surgery is crucial for maintaining function. Seaweed-derived scaffold materials, with their resemblance to oral tissue structure, promote cell adhesion and differentiation. Their high porosity aids in exudate absorption, reducing infection risks and tissue maceration.

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Article Synopsis
  • - The study explores the potential use of green-synthesized copper nanoparticles (CuNPs) made from Acanthophora sp., a marine macroalgae known for its medicinal properties, in anticoagulation therapy.
  • - CuNPs were confirmed through various analyses like UV-vis spectroscopy, SEM, and FT-IR, showing a surface plasmon resonance peak and specific functional groups indicative of their formation and purity.
  • - The results indicated that these CuNPs effectively increase blood clotting time, with notable anticoagulant effects at a concentration of 100 μg/mL, suggesting they could serve as a natural blood thinner.
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Background Copper and copper oxide nanoparticles synthesized by green methods have attracted considerable attention due to their environmentally friendly properties and potential applications. Green synthesis involves non-hazardous and sustainable techniques used in the production of a wide range of substances, including nanoparticles, pharmaceuticals, and chemicals. These methods often use different organisms, including bacteria, fungi, algae, and plants, each offering different advantages in terms of simplicity, cost-effectiveness, and environmental sustainability.

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Introduction Marine actinobacteria are promising sources of novel bioactive compounds due to their distinct ecological niches and diverse secondary metabolite production capabilities. Among these,  sp. T3S11 is notable for its unique spore chain structure, which allows for both morphological and genetic identification.

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Background Currently, nanotechnology is a rapidly advancing field of research. Because of their nanoscale dimensions, nanoparticles (NPs) find application in a wide range of industries, including engineering and medicine. The leaves of have anti-inflammatory qualities.

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Introduction The utilization of for the eco-friendly synthesis of zinc oxide nanoparticles, which contain distinguishable nanostructures, presents a cost-effective and environmentally sustainable alternative for producing zinc nanoparticles. The production process of zinc nanoparticles are rich in phytochemicals, which can serve as stabilizing and reducing agents. Zinc nanoparticles can easily pass through bacterial cell walls and reach all cellular components.

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Background: In today's world, antibiotic-resistant microorganisms are a major concern. There is solid evidence that metal nanoparticles (NPs) tend to have antimicrobial properties. The most effective substitute for antibiotic resistance is the incorporation of metal NPs.

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Background The biosynthesis of nanoparticles represents a rapid, environmentally friendly, cost-effective, and straightforward technology. This approach allows for the production of nanoparticles with a wide range of chemical compositions, sizes, shapes, high uniformity, and scalability. One of the principal advantages of biogenic nanoparticles is their water solubility and compatibility with biological systems.

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Heavy metal pollution has significant impacts on aquatic fauna and flora. It accumulates in marine organisms, both plants and animals, which are then consumed by humans. This can lead to various health problems, such as organ damage and the development of cancer.

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Background: Scientists are currently investigating ecologically sound and enduring techniques for nanoparticle production. Utilizing natural sources such as plant extracts provides an environmentally friendly and economically efficient method. , also referred to as the gray mangrove, is predominantly located in coastal regions.

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Introduction: The extracts derived from red seaweed have shown characteristics that may reduce inflammation. The abovementioned effects can potentially provide positive outcomes in managing inflammatory illnesses, including arthritis, inflammatory bowel disease, and other skin problems.

Aim: The polysaccharides were isolated from the  species.

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Aim: Silver nanoparticles (AgNPs) are considered to be a very significant and intriguing type within the category of metallic nanoparticles, particularly in the context of their involvement in biological applications. The objective of this research is to use the green synthesis method in order to synthesize AgNPs by using the leaf extract of . Furthermore, the study aims to evaluate the antioxidant and anti-inflammatory properties of these nanoparticles.

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The present investigation is the first of its kind which aims to study the characteristics of microbial consortium inhabiting one of the natural high background radiation areas of the world, Chavara Coast in Kerala, India. The composition of the microbial community and their structural changes were evaluated under the natural circumstances with exorbitant presence of radionuclides in the sediments and after the radionuclide's recession due to mining effects. For this purpose, the concentration of radionuclides, heavy metals, net radioactivity estimation via gross alpha and beta emitters and other physiochemical characteristics were assessed in the sediments throughout the estuarine stretch.

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Background: Marine macroalgae is consumed by individuals in several regions, including Scandinavia, Great Britain, Ireland, China, and Japan; in Japan, it is commonly referred to as aosa. Copper nanoparticles are primarily composed of copper and exhibit a size distribution ranging from 1 to 100 nm. Copper nanoparticles can be synthesized using chemical or natural means, similar to other nanoparticle variants.

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Article Synopsis
  • The extensive use of plastics has made them integral to modern society due to their versatility and cost-effectiveness, but this has resulted in environmental issues related to the proliferation of microplastics (MPs).
  • MPs, originating from sources like textile fibers and cosmetics, are concerning because they can accumulate in the food chain and pose risks to human health.
  • The review discusses various analytical techniques for detecting MPs and emphasizes the need for standardized methods to improve identification and quantification while addressing the ongoing challenges in studying microplastics in the environment and food sources.
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Introduction The field of nanotechnology is currently being extensively researched. Nanoparticles (NPs) are used in many fields, such as engineering and medicine, owing to their nanoscale dimensions. Zinc (Zn) appears to be the most desirable metal NP, as it is being applied in various drug delivery systems and other fields.

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Seafood is a valuable nutritional source, but it is highly susceptible to bacterial contamination, posing a severe health risk to humans. Enterotoxin-producing genes carrying Staphylococcus sp. are a significant concern in marine fish.

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The present study explores the antifouling potentials of ethanol extract of mangrove . Results of antibacterial activity inferred that extract had strongly inhibited the growth of fouling bacterial strains with significant differences in halos (9-16 mm) and showed minimal bacteriostatic (12.5-100 µg ml) and bactericidal (25-200µg ml) values.

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Microbially influenced corrosion (MIC) of metals is an important industrial problem, causing 300-500 billion dollars of economic loss worldwide each year. It is very challenging to prevent or control the MIC in the marine environment. Eco-friendly coatings embedded with corrosion inhibitors developed from natural products may be a successful approach for MIC prevention or control.

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The present study aimed to determine the extended spectrum beta lactamase (ESBL) genes in the bacteria from fresh exportable fish samples collected along South east coast of India, Chennai. ESBL genes are the base for the antibiotic resistance in pathogens and it transmitted from one to other species. Totally 2670 isolates were isolated from 293 fish samples which belong to 31 species dominated by Aeromonas, Klebsiella, Serratia, Leclerica, Proteus, Enterobacter, Acinetobacter, Haemophilus, Escherichia, Shigella sp.

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In the present study, the green synthesis of silver nanoparticles (AgNPs) using ethanol extract of Cymodocea serrulata and biological activity were investigated by UV-visible spectrophotometer, Fourier-transform infrared spectroscopy (FTIR), x-ray powder diffraction (XRD), and scanning electron microscopy. The results show that nanoparticles synthesized were confirmed by color change from green to dark brown. The XRD analysis confirmed that the AgNPs were crystalline and found that their UV maximum specific absorbance was between 200 and 400 nm, and their field emission scanning electron microscopy size was between 60 and 69 nm.

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