Publications by authors named "Pishchulov Konstantin"

Introduction: Postoperative venous thromboembolism (VTE) is a frequently occurring complication among glioma patients. Several risk assessment models (RAMs), including the Caprini RAM, the IMPROVE Risk Score, the IMPROVED VTE Risk Score, and the Padua Prediction Score, have not been validated within the glioma patient population. The purpose of this study was to assess the predictive accuracy of established VTE risk scales in patients with glioma.

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Article Synopsis
  • The study established reference intervals (RIs) and analyzed biological variability (BV) to facilitate the introduction of the thrombin generation test (TGT) into clinical practice.
  • It involved testing platelet-poor plasma (PPP), platelet-rich plasma (PRP), and microparticle-mediated TGT in healthy participants, utilizing nested ANOVA for BV evaluation across multiple weeks.
  • Results indicated varying degrees of individual and analytical variation for TGT parameters, leading to recommended RIs for evaluating thrombin generation based on PPP and PRP, with important implications for clinical monitoring.
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Introduction: Patients with glioma (GM) are at a high risk of venous thromboembolism (VTE). The role of microvesiculation in the cancer-associated thrombosis mechanisms has been previously demonstrated. This study aimed to evaluate the relative abundance of extracellular vesicles (EVs) and thrombin generation (TG) in combination with standard laboratory tests in patients with newly diagnosed GM as potential prognostic markers in VTE.

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A 58-year-old male patient with multi-vessel pulmonary vein (PV) stenosis following atrial fibrillation ablation was referred to a specialized pulmonary hypertension clinic. Chest dual-energy computed tomography (CT)-angiography allowed precise diagnosis of two PVs occlusion and three PVs significant stenosis. Iodine maps showed perfusion deficiency and its value for each stenosis, determining the sequence of multiple PV interventions.

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