Publications by authors named "Pious Appiah"
Article Synopsis
- Older adults in nursing and care homes are at significant risk of severe RSV infections, leading to high rates of hospitalization and mortality.
- A systematic study gathered data from multiple research databases and included 20 relevant studies that highlighted varying incidence and case fatality rates of RSV among this population.
- Common pre-existing health issues linked to higher RSV risk included chronic respiratory and cardiovascular conditions, diabetes, and dementia, indicating the importance of monitoring these individuals closely for RSV infections.
Article Synopsis
- - The study compared Sanger sequencing and next-generation sequencing (NGS) to detect drug-resistance mutations in HIV-1 among treatment-naive patients in Ghana, aiming to find minority mutations that could lead to treatment failure.
- - NGS identified 25 mutations in the HIV genes compared to 21 by Sanger sequencing, revealing a higher detection rate of minority drug resistance mutations (55% vs. 35%).
- - Results suggest NGS is more effective for accurate drug resistance testing and highlight the need for its implementation in clinical settings in Ghana, as Sanger sequencing alone may miss significant mutations.