Protective effect of local temporary ischemia depends on applied dose of radiation.

The aim of this study was to verify hypothesis that protective effect of local temporary ischemia depends on dose of radiation. 56 male WAG-strain rats were used. Total body irradiation with 3 x 3 and 3 x 5 Gy was performed.

[Radiotherapy as prevention of heterotopic ossification--preliminary results].

Heterotopic ossification is a common complication of hip arthroplasty (35-57%) and multifragmental acetabular fractures (50-70%). Due to complication level and cost of surgery in this region, more popular become methods of heterotopic ossification prevention as well as non-steroid anti inflammatory drug intake and radiotherapy (approximately 90% effectiveness in high risk groups). Presented material comprises 22 cases irradiated using a dose of 6-7 Gy delivered in one fraction to prevent ossification or to stop active process.

Post-dilatation intravascular brachytherapy trials on hypercholesterolemic rabbits using 32P-phosphate solutions in angioplasty balloons.

Purpose: Response of peripheral arteries to post-dilatation intravascular brachytherapy (IVBT) using 32P liquid sources was studied in a rabbit model.

Methods: The applied sources were angioplasty balloons filled with aqueous solutions of Na2H32PO4, NaCl and iodinated contrast. Dose distribution was calibrated by thermoluminescence dosimetry.

32P liquid sources--comparison of the effectiveness of postangioplasty versus poststenting intravascular brachytherapy in hypercholesterolemic rabbits. Adjunctly implanted titanium stent does not attenuate the effect of endovascular irradiation.

Purpose: Endovascular application of ionizing radiation is a promising but still not sufficiently studied means of restenosis prevention. To test the effects of radiation on restenosis, and especially their dependence on whether the angioplasty was followed by stent implantation or not, we performed an in-stent versus no-stent intravascular brachytherapy study in an animal model. Balloon-based, continuous and self-centering, liquid 32P sources seemed the most convenient for the purpose.

[Interventional treatment of myocardial infarction. Own experience].

Unlabelled: The aim of the study is the analysis of own results of myocardial infarction treatment using percutaneous coronary intervention (PCI) in the setting of twenty-four hour long hemodynamic service. Between 01.12.

Endovascular gamma irradiation of the iliac arteries: 1-year results from a clinical safety and feasibility study.

Purpose: To estimate safety and feasibility of vascular brachytherapy in iliac arteries.

Methods: Fourteen patients (11 men; mean age 56.7+/-9.

[Regulation of intracellular processes by fatty acids and end products of lipid peroxidation].

Products of ingested fat metabolism and also products of lipid peroxidation influenced on genes expression being natural ligands for nuclear receptors functioning as a transcription factors. This situation creates possibilities of diet modification by type and amount of fat as an important element of cancer prevention and cancer therapy. Functioning and activity of PPARs indicating the way of controlling their activity by another ligands than that included in the diet.

Lipid peroxidation and vitamin E in human coronary atherosclerotic lesions.

Background: We aimed to assess the oxidant/antioxidant status within the ex vivo human coronary endarterectomy samples.

Methods: To achieve this, we measured products of lipid oxidation (malondialdehyde, 7-ketocholesterol), lipids (cholesterol, cholesteryl esters) and vitamin E in endarterectomy samples.

Results: Content of malondialdehyde in the plaque ranged from 0.

Vascular brachytherapy after percutaneous transluminal angioplasty of superficial femoral arteries-Polish pilot group.

Purpose: The article presents the results of treatment with vascular brachytherapy (VBT) in superficial femoral arteries. This method aims to minimize frequency of restenosis after percutaneous transluminal angioplasty (PTA).

Method: Treatment was carried out in 20 cases.

Post-stenting intravascular brachytherapy trials on hypercholesterolemic rabbits using 32P liquid sources: implications for prevention of in-stent restenosis.

Purpose: Liquid sources of radiation delivered in angioplasty balloons may be a convenient self-centering device used for prevention of in-stent restenosis. To test the effectiveness of this method an intravascular brachytherapy study was performed using 32P liquid sources in an animal model.

Methods: The radial dose distribution around angioplasty balloons filled with solutions of Na 2H 32PO 4 was calibrated by thermoluminescence dosimetry.