Publications by authors named "Piotr P Szczypa"
Background And Objective: Dupuytren's contractures affecting proximal interphalangeal (PIP) joints are challenging to treat. We explored the effects of collagenase Clostridium histolyticum (CCH) on PIP joint contractures after injection of an affected metacarpophalangeal (MP) joint in the same finger and after injection of an isolated PIP joint contracture.
Methods: Two patient subsets were evaluated: those with MP/PIP joints contractures in the same finger, but only the MP joint contractures were treated (Group A); and those with isolated PIP joint contractures that were treated (Group B).
Article Synopsis
- Dupuytren's disease (DD) is a common but often overlooked condition affecting the hand's fascia, leading to joint contractures, and its prevalence increases with age due to an aging global population.
- Patients with DD seek help from various healthcare providers, highlighting the need for clear guidelines on recognizing symptoms, evaluating risk factors, and understanding when to refer for treatment.
- A large European study shows that general practitioners often diagnose and refer DD cases, but there are significant differences across countries influenced by various factors, emphasizing the importance of early diagnosis and treatment for better outcomes.
Collagenase Clostridium histolyticum (CCH) is a non-surgical, efficacious therapy for Dupuytren's contracture (DC). This study evaluated the efficacy and safety of CCH in patients with previous DC surgery. Data from 12 CCH clinical trials were pooled.
View Article and Find Full Text PDFINTRODUCTION: Dupuytren's disease (DD) causes progressive digital flexion contracture and is more common in men of European descent. METHODS: Orthopaedic and plastic surgeons in 12 European countries (the Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, The Netherlands, Poland, Spain, Sweden and the UK) with >3 and <30 years experience reviewed the medical charts of five consecutive patients they had treated surgically for DD in 2008. Descriptive statistics are reported.
View Article and Find Full Text PDFArticle Synopsis
- Dupuytren's disease (DD) primarily affects European men and is mostly treated surgically, with a survey conducted among 687 surgeons in 12 European countries to understand treatment methods and factors influencing surgical choices.* -
- The survey revealed different surgical procedures used: 37% performed percutaneous needle fasciotomy, 77% fasciotomy, 95% fasciectomy, and 40% dermofasciectomy, with the complexity of the procedure affecting physical therapy prescriptions and recurrence rates.* -
- Fasciectomy emerged as the preferred procedure due to its association with lower recurrence rates compared to other methods like PNF and fasciotomy, emphasizing the importance of patient and surgical factors in treatment decisions.*