From a systems biology perspective, the majority of cancer models, although interesting and providing a qualitative explanation of some problems, have a major disadvantage in that they usually miss a genuine connection with experimental data. Having this in mind, in this paper, we aim at contributing to the improvement of many cancer models which contain a proliferation term. To this end, we propose a new non-local model of cell proliferation.
View Article and Find Full Text PDFThe dynamics of the infectious disease transmission are often best understood by taking into account the structure of population with respect to specific features, for example age or immunity level. The practical utility of such models depends on the appropriate calibration with the observed data. Here, we discuss the Bayesian approach to data assimilation in the case of a two-state age-structured model.
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