Publications by authors named "Pintoo Kumar Niraj"

Article Synopsis
  • Groundwater arsenic poisoning is a significant health risk, especially in Bihar, where a study evaluated arsenic ingestion from breastmilk in a pediatric population.
  • Out of 513 women, 378 provided breastmilk, revealing that 55% had arsenic levels in their milk above the WHO permissible limit, with 67% of infants also displaying elevated urine arsenic levels.
  • The study highlights a concerning 50% elimination rate of arsenic in infants and identifies staple foods like rice and potatoes as major contamination sources, calling for urgent legislative action to combat this serious health threat.
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Article Synopsis
  • - The study in Kaliprasad village, Bihar, examined the health effects of arsenic exposure on 102 households, analyzing their water and biological samples using advanced technology.
  • - Results revealed serious health issues among villagers, including skin problems, respiratory issues, diabetes, hypertension, and neurological disorders, with a disturbing percentage of water and urine samples showing high arsenic levels.
  • - The calculated hazard quotient indicated an alarming level of risk for the population, particularly children and females, suggesting they are at a very high risk for diseases related to arsenic exposure.
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In recent times Gallbladder cancer (GBC) incidences increased many folds in India and are being reported from arsenic hotspots identified in Bihar. The study aims to establish association between arsenic exposure and gallbladder carcinogenesis. In the present study, n = 200 were control volunteers and n = 152 confirmed gallbladder cancer cases.

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Fast growing arsenic menace is causing serious health hazards in Bihar, India, with an estimated 10 million people at risk. The exposed population is often unaware of the problem, which only amplifies the burden of arsenic health effects. In the present study, we have assessed the current situation of arsenic exposure in Chapar village of Samastipur district, Bihar.

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Arsenic poisoning through groundwater is the world's greatest normal groundwater catastrophe which got an immense effect on worldwide general wellbeing. India is confronting the outcomes of arsenic poisoning in the zone of Ganga Brahmaputra alluvial plains. In Bihar, out of 38 districts, 18 districts are exceptionally influenced with groundwater arsenic defilement.

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Reportedly, 300 million people worldwide are affected by the consumption of arsenic contaminated groundwater. India prominently figures amongst them and the state of Bihar has shown an upsurge in cases affected by arsenic poisoning. Escalated arsenic content in blood, leaves 1 in every 100 human being highly vulnerable to being affected by the disease.

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Background: In the present times, arsenic poisoning contamination in the ground water has caused lots of health-related problems in the village population residing in middle Gangetic plain. In Bihar, about 16 districts have been reported to be affected with arsenic poisoning. For the ground water and health assessment, Simri village of Buxar district was undertaken which is a flood plain region of river Ganga.

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Objective: The main objective of the current study was to observe the ameliorative effect of Withania somnifera on arsenic-induced testicular toxicity by exploring the crucial parameters such as sperm counts, sperm motility, hormonal assay and lipid peroxidation including histopathology.

Materials And Methods: In the present study, arsenic in the form of sodium arsenite was administered orally to male Charles Foster rats for 45 days. Thereafter, ethanolic root extract of Withania somnifera was administered for 30 days to observe its ameliorative effect on male reproductive system.

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