Publications by authors named "Pinto-Pulido E"
Article Synopsis
- A 13-year-old boy was diagnosed with hypohidrotic ectodermal dysplasia (HED) linked to a genetic mutation in the ectodysplasin A (EDA) gene.
- He presented with small, white papules on his face, particularly around the nose, forehead, and cheeks.
- Histological analysis showed increased sebaceous lobules in the skin, and there's a suggestion that this might be related to a disruption in the Wnt/β-catenin signaling pathway due to the EDA issue.
With the introduction of large-scale COVID-19 vaccination programs, a variety of cutaneous manifestations have been described. We present two girls (ages 12 and 5 years) who developed erythema nodosum (EN) 3 and 14 days after Pfizer-BioNTech COVID-19 vaccination, respectively. While EN after COVID-19 vaccination has been reported in adults, it is can also occur in children.
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- Apremilast is an oral medication used to treat psoriasis, psoriatic arthritis, and oral ulcers in Behçet's disease, with a study analyzing its use among 41 patients in relation to biological treatments.
- The majority of patients (85.4%) took apremilast for psoriasis, often due to inadequate results from previous treatments, and the medication's continuation wasn't significantly affected by prior biologic use.
- The main reason for stopping apremilast was lack of effective disease control (60.0%), with many patients transitioning to biologic therapies thereafter.