Highly Efficient Spintronic Terahertz Emitter Utilizing a Large Spin Hall Conductivity of Type-II Dirac Semimetal PtTe.

The remarkable spin-charge interconversion ability of transition metal dichalcogenides (TMDs) makes them promising candidates for spintronic applications. Nevertheless, their potential as spintronic terahertz (THz) emitters (STEs) remains constrained mainly due to their sizable resistivity and low spin Hall conductivity (SHC), which consequently result in modest THz emission. In this work, the TMD PtTe, a type-II Dirac semimetal is effectively utilized to develop efficient STEs.

Antimicrobial Screening, in Silico Studies and QSAR of Chalcone-based 1,4-disubstituted 1,2,3-triazole Hybrids.

The in vitro antimicrobial properties of some chalcones (1A-1C: ) and chalcone tethred 1,4-disubstituted 1,2,3-triazoles (2A-2U: ) towards different microbial strains , , , , and are reported. Compounds 2G: and 2U: exhibited better potency than the standard Fluconazole with MIC values of 0.0063 µmol/mL and 0.

Synthesis, antimicrobial potency with in silico study of Boc-leucine-1,2,3-triazoles.

A library of N-Boc protected Leucine-linked 1,4-disubstituted 1,2,3-triazoles was synthesized and fully characterized, in high yield via copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction. In vitro antibacterial activity showed that compound 4h found to be more potent than the reference drug Ciprofloxacin (MIC: 0.0196 µmol/mL) against tested bacterial strains S.

An Fe-doped ZnO/BiVO heterostructure-based large area, flexible, high-performance broadband photodetector with an ultrahigh quantum yield.

Pristine ZnO has been widely explored for its use in UV photodetectors; however, the utility of ZnO in broadband photodetectors is still a challenge as it absorbs in the UV region only with low quantum efficiency and responsivity that can be accredited to the high recombination rate of photo-generated charge carriers. To address this issue, we report an Fe-doped 2D ZnO thin film, obtained through band gap engineering, and a 1D electrospun mixed-inorganic monoclinic BiVO nanofiber heterostructure on an ITO-coated PET substrate-based broadband photodetector (PD) with ultra-high responsivity and EQE values in comparison to PDs fabricated using expensive cleanroom techniques. BiVO plays the dual role of absorbing photons in the visible and NIR regions and creating local electric fields at the interface of the Fe-doped ZnO (FZO)-BiVO heterostructure, which helps in the separation of electron-hole pairs.

Synthesis, crystal structure and antimicrobial potential of some fluorinated chalcone-1,2,3-triazole conjugates.

A simple and green synthesis of some fluorinated chalcone-triazole hybrids from propargylated chalcones and organic azides catalyzed by cellulose supported copper nanoparticles click reaction is reported. All the synthesized compounds were well characterized by various analytical and spectroscopic methods. The X-rays crystallographic study of compounds 6k revealed the self assembling properties.

Design, synthesis, characterization, antimicrobial evaluation and molecular modeling studies of some dehydroacetic acid-chalcone-1,2,3-triazole hybrids.

A series of new dehydroacetic acid chalcone-1,2,3-triazole hybrids as potential antimicrobial agents was designed, synthesized and characterized by FTIR, NMR and HRMS spectral techniques. All the synthesized compounds were screened in vitro against four bacterial strains (Staphylococcus epidermidis, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa) and two fungal strains (Aspergillus niger and Candida albicans). The antimicrobial results indicated that some of the compounds showed remarkable activities comparable to the standard drugs.

Green synthesis and anticancer potential of chalcone linked-1,2,3-triazoles.

A series of chalcone linked-1,2,3-triazoles was synthesized via cellulose supported copper nanoparticle catalyzed click reaction in water. The structures of all the compounds were analyzed by IR, NMR and Mass spectral techniques. All the synthesized products were subjected to 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cytotoxicity assay against a panel of four human cancer cell lines (MCF-7, MIA-Pa-Ca-2, A549, HepG2) to check their anticancer potential.

Recent Advancements in 1,4-Disubstituted 1H-1,2,3-Triazoles as Potential Anticancer Agents.

Cancer is a class of formidable disease with high degree of mortality. Despite much progress in chemotherapy, the problem of drug resistance has led to the search for newer leads with superior efficacy. 1,2,3- Triazoles are among a vast number of nitrogen containing heterocycles studied extensively as pharmacologically important scaffolds.