Development and validation of a clinic-radiological model to predict tumor spread through air spaces in stage I lung adenocarcinoma.

Objectives: Tumor spread through air spaces (STAS) is associated with poor prognosis and impacts surgical options. We aimed to develop a user-friendly model based on 2-[F] FDG PET/CT to predict STAS in stage I lung adenocarcinoma (LAC).

Materials And Methods: A total of 466 stage I LAC patients who underwent 2-[F] FDG PET/CT examination and resection surgery were retrospectively enrolled.