Correlation between the expression of CD24 on circulating tumor cells and prognosis in breast cancer.

Objective: To investigate the expression of tumor stem cell marker CD24 in peripheral blood circulating tumor cells (CTCs) of breast cancer and the value of CTCs in predicting the prognosis of breast cancer patients.

Methods: Clinical data of 102 breast cancer patients from January 2015 to December 2019 were retrospectively collected. CTC test results, CD24 test results, tumor size, tumor stage, pathological type, molecular type, lymph node metastasis, survival time, and survival status of patients were collected.

PTPRT Could Be a Treatment Predictive and Prognostic Biomarker for Breast Cancer.

The role of PTPRT in breast cancer was not comprehensively explored and well analyzed. Our study comprehensively searched available databases to analyze the clinical role of PTPRT in breast cancer. We found PTPRT was an antioncogene and could be used to distinguish different stages, age groups, molecular types, and grades for breast cancer.

[Correlation between circulating tumor cells and clinicopathological features of early breast cancer].

To investigate the correlation between the number of peripheral blood circulating tumor cells (CTCs) and clinicopathological features of early breast cancer. 
 Methods: The clinical and pathological data from 100 patients with early breast cancer treated by a breast cancer treatment team in the Department of Breast Surgery, Second Xiangya Hospital, Central South University, were collected from January 2017 to December 2018. For these patients, their peripheral blood CTCs were detected, enumerated and typed by CanpatrolTM CTC assay.

Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium.

The role of exosomes shed from Mycobacterium avium sp. paratuberculosis-infected macrophages in intercellular communication processes was examined. We compared the responses of resting macrophages infected with M.

[Changes of cytokines and protein expression of macrophages stimulated with exosome from macrophages by Mycobacterium avium infection].

Objective: To explore the mechanism underlying the molecular immune response of macrophages stimulated with exosome [(+)exosome] from macrophages after Mycobacterium avium (M. avium) infection and analyze the differential protein component of the exosome.

Methods: The culture supernatants of M.

Overexpression of DEP domain containing mTOR-interacting protein correlates with poor prognosis in differentiated thyroid carcinoma.

DEP domain containing mammalian target of rapamycin (mTOR)-interacting protein (DEPTOR), a recently identified mTOR-interacting protein, is a novel candidate oncogene. Previous studies reveal that high DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. However, its significance in differentiated thyroid carcinoma (DTC) is not yet known.