Publications by authors named "Ping-Ping Lai"
Background: The exact regulation network of programmed death 1 (PD-1), programmed death ligand 1 (PD-L1), and programmed death ligand 2 (PD-L2) signaling in immune escape is largely unknown. We aimed to describe the gene expression profiles related to PD-1 as well as its ligands PD-L1 and PD-L2, thus deciphering their possible biological processes in hepatocellular carcinoma (HCC).
Aim: To find the possible mechanism of function of PD-1, PD-L1, and PD-L2 in HCC.
[Study on differentiation of human mesenchymal stem cells into epidermal cells].
Zhonghua Shao Shang Za Zhi
February 2007
Objective: To investigate the possibility of differentiation of human mesenchymal stem cells (hMSC) into epidemic cells in vitro.
Methods: hMSCs were segregated from normal adult human bone marrow by Percoll solution (1.073 g/ml) , and were cultured, purified, and amplified to 3th passage in vitro.
Article Synopsis
- - The study focuses on the potential of human bone marrow-derived mesenchymal stem cells (hMSCs) to differentiate into epidermal-like cells in vitro under specific conditions.
- - Researchers found that when exposed to an inducing medium, hMSCs expressed key markers associated with epidermal cells and changed their morphology, indicating successful differentiation.
- - The findings suggest that hMSCs have multipotential capabilities, opening new avenues for research into their applications in skin-related therapies and regenerative medicine.
[Isolation, culturation and adipogenisis committed differentiation of adult human mesenchymal stem cell].
Zhejiang Da Xue Xue Bao Yi Xue Ban
April 2003
Objective: To isolate MSCs from adult human bone marrow cells and to induce them into adipocytes.
Methods: MSCs were isolated from adult human bone marrow aspirated by Percoll and expanded in L-DMEM. The surface antigen of MSCs, CD14, CD34, CD45, CD44, VLA-1, HLA-DR and cell cycle were analysed on a FACScan flow cytometer.