Publications by authors named "Ping-Hsuan Chiang"
Article Synopsis
- Epithelial ovarian cancer (EOC) is the most prevalent form of ovarian cancer, and HOXD10 downregulation has been linked to increased tumor migration and invasion, although the details of its regulation are still unclear.
- The study found that overexpressing HOXD10 in EOC cells reduced their growth and movement, and identified gene expression changes associated with this overexpression using various bioinformatics tools.
- The analysis revealed that genes linked to oxidative phosphorylation and mitochondrial function were affected, suggesting a connection between HOXD10 and cancer metabolism, which could inform new treatment strategies targeting metabolic pathways to combat drug resistance in ovarian tumors.
Glutathione (GSH) is a major antioxidant in organisms. An alteration in GSH concentration has been implicated in a number of pathological conditions. Therefore, GSH sensing has become a critical issue.
View Article and Find Full Text PDFObjective: Operative hysteroscopy is a common gynecologic procedure, but it carries the risk of complications. Spontaneous small intestine perforation is rare and fatal, especially in young adults. We present a spontaneous small intestine perforation after operative hysteroscopy with mimicking sign of uterine perforation after operation hysteroscopy.
View Article and Find Full Text PDFPAST: Most prostate cancers are slow growing and are often diagnosed at an old age, which may result in treatment never being needed. However, definitive treatments such as radical prostatectomy and radiation therapy are often associated with many serious adverse effects, harming the physical and mental health of patients. PRESENT: In recent years, different types of minimally invasive therapy have been developed to achieve cancer control, continence, and even potency preservation, such as high-intensity focused ultrasound (HIFU).
View Article and Find Full Text PDFPurpose: We reported preliminary outcomes of high-intensity focused ultrasound (HIFU) [Sonablate] in the combination of transurethral resection of the prostate for localized prostate cancer in Taiwan.
Methods: Seventy-seven patients using Sonablate HIFU for localized prostate cancer were enrolled in this study from April 2021 to December 2022. Prostate-specific antigen biochemical recurrence, International Index of Erectile Function (IIEF)-5 scores, International Prostate Symptom Score (IPSS), quality of life (QoL) scores, and postoperative complications were recorded during follow-up.