Exploring the growing phase forest musk deer () dietary energy requirements based on growth performance and gut microbiota analysis.

Unlabelled: The forest musk deer (FMD) farming industry is currently experiencing rapid growth, yet the dietary energy requirements for FMD remain unclear. Therefore, we explored the optimal dietary digestible energy (DE) for growing phase FMD by providing three diets with different DE levels and analyzing changes in gut microbiota. A total of 20 six-month-old FMD were used in a 62-day trial.

[Effects of By-products of Co-pyrolysis on Biochar for Benzene Vapor Adsorption Performance].

To explore the effects of the components in the raw materials and by-products of co-pyrolysis on the physicochemical properties of biochar, rice husk （RH, which has a high percentage of lignin and a low content of N） and sawdust （SD, which has a high percentage of both cellulose and N） were used as typical raw materials to prepare co-pyrolysis biochar. The benzene vapor adsorption performance of the obtained biochar was then tested on a fixed-bed device. At the same time, the by-product components generated during pyrolysis were analyzed using thermogravimetric （TG）, scanning electron microscopy （SEM）, and gas chromatography-mass spectrometry （GC-MS）.

The Specific Impacts of Allelopathy and Resource Competition from on the Growth of Three Plant Species in Northern China.

Plant interference is a key factor influencing plant coexistence and species composition. The two primary forms of plant interference-allelopathy and resource competition-are often difficult to separate. This study conducted an outdoor pot experiment to quantify the distinct contributions of resource competition and allelopathy of on seedling growth of three species: , , and .

A predictive nomogram for mutation status in lung adenocarcinoma manifesting as ground-glass nodules.

Background: The mutation status of epidermal growth factor receptor () in lung adenocarcinoma is significantly associated with postoperative progression-free survival. Computed tomography (CT)-based radiomics analysis may have potential value in predicting mutation status. This study aims to explore the predictive capacity of radiomics analysis for mutation status in lung adenocarcinomas presenting as ground-glass nodules (GGNs).

RAD52 and ERCC6L/PICH have a compensatory relationship for genome stability in mitosis.

Mammalian RAD52 is a DNA repair factor with strand annealing and recombination mediator activities that appear important in both interphase and mitotic cells. Nonetheless, RAD52 is dispensable for cell viability. To query RAD52 synthetic lethal relationships, we performed genome-wide CRISPR knock-out screens and identified hundreds of candidate synthetic lethal interactions.

CsWRKY53 and CsWRKY40 synergistically regulate L-theanine hydrolysis by abscisic acid signaling pathway during tea withering.

L-Theanine hydrolysis in tea leaves not only reduces tea product quality but also decreases their health benefits. Postharvest dehydration-induced abscisic acid (ABA) contributes to the L-theanine hydrolysis, but the specific mechanism is unexplored. Based on transcriptome analysis and gene silencing experiments, CsNCED3a was shown to be a key gene for ABA synthesis in harvested tea leaves, and CsABF7 up-regulated the expression of CsWRKY40, a transcription factor (TF) that directly regulates a L-theanine hydrolysis gene, resulting in the loss of L-theanine.

Controlled Synthesis of Graphdiyne-Based Multiscale Catalysts for Energy Conversion.

Graphdiyne (GDY) science is a new and rapidly developing interdisciplinary field that touches on various areas of chemistry, physics, information science, material science, life science, environmental science, and so on. The rapid development of GDY science is part of the trend in development of carbon materials. GDY, with its unique structure and fascinating properties, has greatly promoted fundamental research toward practical applications of carbon materials.

A chromosome-level genome assembly of Cape hare (Lepus capensis).

The Cape hare (Lepus capensis) is among the most widely distributed hare species globally, inhabiting extensive regions across Africa, the Middle East, and Central Asia. However, evolutionary and genetic research on L. capensis was seriously impeded by the absence of a reference genome.

Detection of "smoke powder" etomidate and its metabolite etomidate acid in blood and urine by UHPLC-MS-MS: application in authentic cases.

Recently, etomidate has been widely used as an alternative in illicit drug market. It is usually added to regular cigarette tobacco (commonly known as "cigarette powder") or mixed in e-cigarette oil sold through the Internet, retail stores, or entertainment outlets and other channels. An ultra-high performance liquid chromatography tandem mass spectrometry method was developed to quantify etomidate and etomidate acid in human blood and urine.

Combined CT-Based Radiomics and Clinic-Radiological Characteristics for Preoperative Differentiation of Solitary-Type Invasive Mucinous and Non-Mucinous Lung Adenocarcinoma.

Purpose: The clinical, pathological, gene expression, and prognosis of invasive mucinous adenocarcinoma (IMA) differ from those of invasive non-mucinous adenocarcinoma (INMA), but it is not easy to distinguish these two. This study aims to explore the value of combining CT-based radiomics features with clinic-radiological characteristics for preoperative diagnosis of solitary-type IMA and to establish an optimal diagnostic model.

Methods: In this retrospective study, a total of 220 patients were enrolled and randomly assigned to a training cohort (n = 154; 73 IMA and 81 INMA) and a testing cohort (n = 66; 31 IMA and 35 INMA).

Molecular evolution of intestinal-type early gastric cancer according to Correa cascade.

Early screening is crucial for the prevention of intestinal-type gastric cancer. The objective of the current study was to ascertain molecular evolution of intestinal-type gastric cancer according to the Correa cascade for the precise gastric cancer screening. We collected sequential lesions of the Correa cascade in the formalin-fixed and paraffin-embedded endoscopic submucosal dissection-resected specimens from 14 Chinese patients by microdissection, and subsequently determined the profiles of somatic aberrations during gastric carcinogenesis using the whole exome sequencing, identifying multiple variants at different Correa stages.

Reversible cold-induced lens opacity in a hibernator reveals a molecular target for treating cataracts.

Maintaining protein homeostasis (proteostasis) requires precise control of protein folding and degradation. Failure to properly respond to stresses disrupts proteostasis, which is a hallmark of many diseases, including cataracts. Hibernators are natural cold-stress adaptors; however, little is known about how they keep a balanced proteome under conditions of drastic temperature shift.

Constructing CO-immune water dissociation sites around Pt to achieve stable operation in high CO concentration environment.

The serious problem of carbon monoxide (CO) poisoning on the surface of Pt-based catalysts has long constrained the commercialization of proton exchange membrane fuel cells (PEMFCs). Regeneration of Pt sites by maintaining CO scavenging ability through precise construction of the surface and interface structure of the catalyst is the key to obtaining high-performance CO-resistant catalysts. Here, we used molybdenum carbide (MoC) as the support for Pt and introduced Ru single atoms (SA-Ru) at the Pt-MoC interface to jointly decrease the CO adsorption strength on Pt.

Subjective impressions with myopia control contact lenses versus single vision lenses: A systematic review and meta-analysis.

Purpose: To gain insight into patients' visual experiences and satisfaction when using different forms of myopia control lenses.

Methods: PubMed, Cochrane Library, Embase, Scopus and Web of Science databases were searched for articles assessing subjective visual quality with myopia control lenses compared with single-vision lenses (SVLs) up to July 10, 2023. Eight-hundred-and-three articles were retrieved, reviewed and any questionnaire items on subjective impressions of lens wear were meta-analysed.

Distinct functions of PAXX and MRI during chromosomal end joining.

A key step of Canonical Nonhomologous End Joining (C-NHEJ) is synapsis of DNA double strand break (DSB) ends for ligation. The DNA-PKcs dimer mediates synapsis in a long-range complex with DSB ends remaining apart, whereas the XLF homodimer can mediate synapsis in both long-range and short-range complexes. Recent structural studies found the PAXX homodimer may also facilitate synapsis in long-range complexes with DNA-PKcs via its interactions with Ku70.

Deciphering the role of rhizosphere microbiota in modulating disease resistance in cabbage varieties.

Background: Cabbage Fusarium wilt (CFW) is a devastating disease caused by the soil-borne fungus Fusarium oxysporum f. sp. conglutinans (Foc).

Pathological characteristics analysis of children with intermittent and persistent hydronephrosis due to uretero-pelvic junction obstruction.

Objective: To analyze from a pathological perspective the differences between intermittent and persistent hydronephrosis in children with uretero-pelvic junction obstruction.

Methods: 23 children who underwent unilateral dismembered pyeloplasty (Anderson-Hynes operation) for intermittent hydronephrosis from September 2017 to March 2024 were included in the observation group. They were compared with a control group consisting of 23 children with persistent hydronephrosis matched for age, gender, and affected side.

Prediction of the Benign or Malignant Nature of Pulmonary Pure Ground-Glass Nodules Based on Radiomics Analysis of High-Resolution Computed Tomography Images.

To evaluate the efficacy of radiomics features extracted from preoperative high-resolution computed tomography (HRCT) scans in distinguishing benign and malignant pulmonary pure ground-glass nodules (pGGNs), a retrospective study of 395 patients from 2016 to 2020 was conducted. All nodules were randomly divided into the training and validation sets in the ratio of 7:3. Radiomics features were extracted using MaZda software (version 4.

Lens autophagy protein ATG16L1: a potential target for cataract treatment.

Cataract is the leading cause of blindness and low vision worldwide, yet its pathological mechanism is not fully understood. Although macroautophagy/autophagy is recognized as essential for lens homeostasis and has shown potential in alleviating cataracts, its precise mechanism remains unclear. Uncovering the molecular details of autophagy in the lens could provide targeted therapeutic interventions alongside surgery.

The Value of Radiomics Features Based on HRCT in Predicting whether the Lung Sub-Centimeter Pure Ground Glass Nodule is Benign or Malignant.

Objective: In this study, a radiomics model was created based on High-Resolution Computed Tomography (HRCT) images to noninvasively predict whether the sub-centimeter pure Ground Glass Nodule (pGGN) is benign or malignant.

Methods: A total of 235 patients (251 sub-centimeter pGGNs) who underwent preoperative HRCT scans and had postoperative pathology results were retrospectively evaluated. The nodules were randomized in a 7:3 ratio to the training (n=175) and the validation cohort (n=76).

Phase noise suppression of optic flexural disk accelerometer by studying the thermal stability of optical fiber ring.

As the core sensing elements of ultra-long fiber interferometer, the distributed thermal strain difference of the fiber rings can cause extra noise of the flexural disk, resulting in a penalty of the deterioration accuracy. In this paper, the thermal strain distribution characteristics of the fiber ring are firstly analyzed by the finite element method (FEM), and the distribution result is consistent with that demonstrated by the Rayleigh optical frequency-domain reflectometry (R-OFDR) strain measurement. The interferometer phase noise caused by the distributed strain difference is further studied by constructing a fully symmetric polarization-maintaining fiber-ring Mach-Zehnder interferometer (MZI) with an arm length of over 100 meters.