() possesses numerous virulence factors, with the increasing prevalence of drug-resistant strains heightening the threat posed by this pathogen. Staphylococcal enterotoxin B (SEB), a highly conserved toxin secreted by , is also recognized as a potential bioweapon with super-antigenic activity. SEB represents a promising target in efforts to combat infections caused by .
View Article and Find Full Text PDFAntimony sulfoselenide (Sb(S,Se)) is a promising sunlight absorber material for solar energy conversion in photovoltaic (PV) cells and photoelectrochemical (PEC) photoelectrodes due to its excellent photoelectric properties. However, the obtained thin-film and back contact properties significantly influence the PEC performance of photocathodes, causing severe bulk recombination, carrier transport loss, and deteriorating half-cell solar-to-hydrogen (HC-STH) efficiency. This study introduces an intriguing dual back interface engineering strategy for Sb(S,Se) photocathodes by incorporating an intermediate MoO layer and a secondary carrier transport channel of Au to strengthen charge carrier dynamics.
View Article and Find Full Text PDFMembranes (Basel)
November 2024
Polyvinylidene fluoride (PVDF) membranes are extensively utilized in membrane distillation (MD) for water treatment. However, traditional methods easily form asymmetrical membranes with dense skin layers that are detrimental to membrane flux. Herein, an eco-friendly PVDF membrane was fabricated by utilizing a delayed phase separation process without using any pore-forming agents.
View Article and Find Full Text PDFObjective: To evaluate the therapeutic effect of sacubitril/valsartan compared to enalapril in managing heart failure (HF) after percutaneous coronary intervention (PCI).
Methods: From January 2018 to December 2021, 63 hospitalized patients diagnosed with HF following acute myocardial infarction (AMI) were enrolled in this prospective clinical trial. The observation group was comprised of 31 patients treated with sacubitril/valsartan (LCZ696) sodium tablets, while the control group, including 32 patients, received enalapril maleate tablets.
Introduction: Traumatic brain injury (TBI) is one of the prevalent critical illnesses encountered in clinical practice, often resulting in a spectrum of consciousness disorders among survivors. Prolonged states of impaired consciousness can significantly elevate the susceptibility to complications such as urinary tract infections and pulmonary issues, consequently leading to a compromised prognosis and substantially impacting the quality of life for affected individuals. Clinical studies have reported that median nerve electrical stimulation (MNES) may have a therapeutic effect in the treatment of disorders of consciousness (DOC).
View Article and Find Full Text PDFACS Appl Mater Interfaces
November 2024
Diagn Microbiol Infect Dis
December 2024
Measuring and analyzing both nonlinear-distortion and linear-reflection otoacoustic emissions (OAEs) combined creates what we have termed a "joint-OAE profile." Here, we test whether these two classes of emissions have different sensitivities to hearing loss and whether our joint-OAE profile can detect mild-moderate hearing loss better than conventional OAE protocols have. 2f1-f2 distortion-product OAEs and stimulus-frequency OAEs were evoked with rapidly sweeping tones in 300 normal and impaired ears.
View Article and Find Full Text PDFFront Public Health
October 2024
IEEE Trans Vis Comput Graph
September 2024
Nowadays, orthodontics has become an important part of modern personal life to assist one in improving mastication and raising self-esteem. However, the quality of orthodontic treatment still heavily relies on the empirical evaluation of experienced doctors, which lacks quantitative assessment and requires patients to visit clinics frequently for in-person examination. To resolve the aforementioned problem, we propose a novel and practical mobile device-based framework for precisely measuring tooth movement in treatment, so as to simplify and strengthen the traditional tooth monitoring process.
View Article and Find Full Text PDFIEEE Trans Image Process
October 2024
Reactive lymphocytes may indicate diseases such as viral infections. Identifying these abnormal lymphocytes is crucial for disease diagnosis. Currently, reactive lymphocytes are mainly manually identified by pathological experts with microscopes and morphological knowledge, which is time-consuming and laborious.
View Article and Find Full Text PDFBackground: Real-time shear wave elastography (SWE) is a non-invasive imaging technique used to measure tissue stiffness by generating and tracking shear waves in real time. This advanced ultrasound-based method provides quantitative information regarding tissue elasticity, offering valuable insights into the mechanical properties of biological tissues. However, the application of real-time SWE in the musculoskeletal system and sports medicine has not been extensively studied.
View Article and Find Full Text PDFZinc is an essential trace element, and impaired zinc homeostasis may be associated with inflammation in patients with diabetic nephropathy (DN). We investigated the influence of zinc level on nod-like receptor nucleotide-binding domain and leucine-rich repeat pyrin-3 domain (NLRP3) inflammasome expression and renal prognosis in patients with DN. We recruited 90 patients definitively diagnosed with DN by renal biopsy and 40 healthy controls.
View Article and Find Full Text PDFGermline pathogenic TP53 variants predispose individuals to a high lifetime risk of developing multiple cancers and are the hallmark feature of Li-Fraumeni syndrome (LFS). Our group has previously shown that LFS patients harbor shorter plasma cell-free DNA fragmentation; independent of cancer status. To understand the functional underpinning of cfDNA fragmentation in LFS, we conducted a fragmentomic analysis of 199 cfDNA samples from 82 TP53 mutation carriers and 30 healthy TP53-wildtype controls.
View Article and Find Full Text PDFLow-oxygen (oxygen concentration below 18.5%) phenomena often occur in the top coal caving working face of ultrathick coal seams, posing a serious threat to the safety of workers. The characteristics of oxygen consumption and gas production at low-constant temperature and the corresponding functional group evolution of residual coal in goaf were studied by temperature-programmed and infrared spectrum experiments.
View Article and Find Full Text PDFAmomum villosum Lour. (A. villosum) is a valuable herbaceous plant that produces the famous traditional Chinese medicine Amori Fructus.
View Article and Find Full Text PDFNonsmall-cell lung cancer (NSCLC) is the most frequent type of lung cancer, with early surgical treatment proving vital for prolonged patient survival. However, precise visualization of NSCLC remains a challenge due to limited molecular imaging probes, the unique anatomical structure of the lungs, and respiratory movement interference. In this study, we investigated the potential utility of CD36, which is highly expressed in NSCLC, as an imaging target.
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