Publications by authors named "Ping Jiang"

Background: Sustained attention deficits were reported more significant in patients with major depressive disorder (MDD) than in healthy controls (HCs), and are pivotal in both the development and aggravation of depression. Childhood trauma is also common in MDD and the exposure to childhood trauma may impede sustained attention and increase the treatment resistance in MDD. However, the underlying neuro-mechanisms link the childhood trauma to sustained attention deficits in MDD remain unclear.

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Remote sensing images play a vital role in domains including environmental monitoring, agriculture, and autonomous driving. However, the detection of targets in remote sensing images remains a challenging task. This study introduces innovative methods to enhance feature extraction, feature fusion, and model optimization.

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Developing smart materials with tunable high-temperature afterglow (HTA) luminescence remains a formidable challenge. This study presents a metal-free doping system using boric acid as matrix and polycyclic aromatic hydrocarbons as dopants. This composition achieves dynamically tunable afterglow combining a bright blue HTA lasting for over ten seconds even at 150°C and an ultra-long yellow room-temperature phosphorescence below 110°C.

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Background: Oroantral fistula (OAF) is a pathological channel formed between the oral cavity and the maxillary sinus. A large size of OAF (≥5 mm) increases the risk of surgical failure, and an optimal surgical approach should be cautiously selected.

Objective: This study aims to characterize the application of nasal endoscopy and buccal fat pad (BFP) flaps to repair large OAFs in patients with odontogenic maxillary sinusitis (OMS).

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Purpose: This study aimed to design and evaluate a prior-knowledge-guided U-Net (PK-UNet) for automatic clinical target volume (CTV) segmentation in postmastectomy radiotherapy for breast cancer.

Methods And Materials: A total of 102 computed tomography (CT) scans from breast cancer patients who underwent postmastectomy were retrospectively collected. Of these, 80 scans were used for training with 5-fold cross-validation, and 22 scans for independent testing.

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  • The study investigates HIPK3 DNA methylation as a potential biomarker for rheumatoid arthritis (RA) and its relationship with clinical indicators in multiple rheumatic diseases.
  • Researchers analyzed methylation levels in 368 participants, using advanced sequencing technology, and discovered that HIPK3 methylation was significantly lower in RA, systemic lupus erythematosus (SLE), and dermatomyositis (DM) compared to healthy controls.
  • Findings indicate a negative correlation between HIPK3 methylation levels and various clinical markers in RA, suggesting HIPK3 hypomethylation could serve as a diagnostic indicator for RA and related diseases.
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  • ZBP1 (Z-DNA binding protein 1) is an immune sensor that activates the NLRP3 inflammasome during viral infections, but this function is inhibited by the herpesvirus pseudorabies virus (PRV) through its VP22 protein.
  • The study reveals that VP22 acts as a virulence factor for PRV, preventing ZBP1 from triggering NLRP3 activation, which would normally help combat the infection.
  • When ZBP1 is deficient, a recombinant PRV lacking VP22 replicates more effectively, indicating that VP22's interference with ZBP1’s function is crucial for PRV's pathogenicity.
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  • NONO is a nuclear protein that plays a role in different biological processes, including the immune response to viruses, particularly in pigs.
  • This study found that swine NONO (sNONO) can inhibit replication of the porcine reproductive and respiratory syndrome virus (PRRSV) by boosting the expression of IFN-β, which is crucial for antiviral responses.
  • The research shows that NONO works by forming a complex with the PRRSV N protein and the IRF3 protein, enhancing IFN-β production and countering PRRSV's negative effects on the immune signaling pathway.
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  • - The study investigates the effects of Zhizi Huangqi Shanzha formula (ZHSF) on liver damage caused by aflatoxin, using methods like blood analysis, liver function tests, and gut microbiota analysis.
  • - Results show that ZHSF improves immune response and liver health in poisoned mice by increasing certain blood cell types, reducing liver damage markers, and restoring normal liver tissue and gut bacteria diversity.
  • - The findings suggest that ZHSF could be a potential treatment to prevent liver injury from aflatoxin by balancing gut microbiota and counteracting oxidative stress.
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  • - Mastitis, caused by lipopolysaccharide (LPS) leading to inflammation, damages mammary tissue; understanding factors that can reduce this inflammation is essential.
  • - Syndecan-3 (SDC3) has potential anti-inflammatory properties by inhibiting leukocyte adhesion and reducing reactive oxygen species, but its role in mastitis is not well understood.
  • - Research showed that overexpressing SDC3 in bovine mammary epithelial cells reduces LPS-induced inflammatory cytokines and affects the NF-κB inflammatory pathway, indicating SDC3's role in managing inflammation in mastitis.
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