A novel porous bioceramic scaffold by accumulating hydroxyapatite spheres for large bone tissue engineering. III: Characterization of porous structure.

Physical characteristics of bone tissue engineering scaffolds, including interconnectivity, microporosity, macroporosity, and pore geometry are known to play a crucial role in bone regeneration. In the present study, three-dimensional (3D) interconnected scaffolds were prepared by accumulating hydroxyapatite (HA) spheres in a titanium mesh tube (ф 1.5 × 3 cm).