Histopathological Effects of Parylene C (poly-chloro-p-xylylene) in the Inner Ear.

Objective: To assess the histopathological effects of parylene C (PC) (poly-chloro-p-xylylene) in the inner ear.

Methods: Nine adult Dunkin Hartley guinea pigs (500-600 g) were included in the study. PC pieces were inserted into the cochlea in the right ear of the animals (study group).

Immunomodulatory effectiveness of azithromycin in prevention of postlaminectomy epidural fibrosis.

Objective: One of the important causes of failed back surgery is the extensive peridural fibrosis collecting in the surgical field after spinal surgeries. Today we know that inflammatory mechanisms mediated by the immune system of the body plays an important role in generation of fibrosis. Azithromycin, a macrolide antibiotic, has proven immunomodulatory effects in various diseases.

Small bowel perforation due to metastatic lung squamous cell carcinoma.

Squamous cell cancer of the lung occurs with early dissemination but clinically significant metastases localized to the small bowel are rare. Small bowel metastasis is a fatal complication usually seen in advanced stages of the disease. In the present study, we report a case of a 65-year-old patient who was admitted to the emergency department with acute abdominal pain and during evaluation was found to have squamous cell carcinoma metastasis to small bowel leading to perforation.

Mitomycin C effect on fibrous adhesions of rabbit temporomandibular joint.

Objective: To evaluate influence of mitomycin C on fibrosis in temporomandibular joints of rabbits with mandibular traction.

Study Design: Twenty rabbits (8 control, 12 mitomycin C group) were included. Titanium screws were placed in the anterior edge of the right masseter tuberosity and the posterior part of the right zygoma.