Publications by authors named "Pinar Aksu Kilicle"
Alpha cypermethrin (α-CYP) is an insecticide, a member of the group of synthetic pyrethroid pesticides. This study aims to assess the histopathological and biochemical subacute effects of α-CYP on the renal tissues of 48 male Spraque-Dawley adult rats. In this study, the rats were divided into six groups: control, α-CYP (10 mg kg), α-CYP (20 mg kg), caffeic acid phenethyl ester (CAPE) (10 µmol kg), α-CYP + CAPE (10 mg kg), and α-CYP + CAPE (20 mg kg) groups.
View Article and Find Full Text PDFPesticides, which adversely affect the critical metabolic processes of organisms, disrupt the physiological balance by specifically targeting enzymes and may lead to such consequences that may lead to death. It provides benefits in agricultural activities. The p53 protein antagonizes bcl-2, an anti-apoptotic protein character, and induces apoptosis by causing mitochondrial membrane permeability.
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- The study aimed to explore the protective effects of red dragon fruit extract (DFE) on gastric ulcers induced by indomethacin in rats, focusing on changes in oxidative stress markers and histopathological findings.
- After treating the rats with DFE and inducing ulcers with indomethacin, the researchers noted significant improvements in oxidative stress levels in the groups that received DFE, particularly at higher doses of 500 mg/kg and 1000 mg/kg.
- The findings suggest that DFE may mitigate gastric damage by lowering harmful markers like MDA and Caspase 3, while enhancing antioxidant levels, indicating a potential natural remedy for those suffering from gastric ulcers caused by NSAID use.
Objectives: The aim of this study is to determine the therapeutic effects of pomegranate seed oil, which is a powerful antioxidant and anti-inflammatory agent, on ovarian-ischemia and reperfusion injury in rats.
Materials And Methods: Fifty-six female albino Wistar rats were divided into 7 equal groups. Group 1; Sham Operation, Group 2; Ischemia, Group 3; Ischemia + Reperfusion, Group 4; Ischemia + Pomegranate 0,32 ml / kg (IP), Group 5; Ischemia + Pomegranate 0.
Our aim was to investigate the effects of Achillea millefolium on wound healing in second-degree burns formed in diabetic rats. This study was conducted at the Kafkas University Experimental Research Center. 20 Sprague Dawley rats were divided into 2 groups.
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