Publications by authors named "Pin-Jing Hui"

Background: Cardiogenic embolism caused by patent foramen ovale (PFO) is a common etiology of cryptogenic stroke (CS), particularly in young and middle-aged patients. Studies about right-to-left shunt (RLS) detection using contrast-enhanced transcranial Doppler (c-TCD) are numerous. According to the time phase and number of microbubbles detected on c-TCD, RLS can be classified and graded.

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Article Synopsis
  • The study investigates the role of matrix metalloproteinases (MMPs) in atherosclerotic plaque progression and rupture, which contributes to acute cerebrovascular events.
  • It analyzes human carotid plaques from surgeries, identifying differences in MMP levels and calcification factors between stable and vulnerable plaques.
  • Findings indicate that higher levels of MMP-2 and MMP-14 are associated with vulnerable plaques, along with factors indicating neovascularization and activation of specific signaling pathways, which could help improve diagnosis and prevention of plaque-related issues.
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Background: Surgical treatment of intracranial aneurysms is often compromised by incomplete exclusion of the aneurysm or stenosis of parent vessels. Intraoperative microvascular Doppler (IMD) is an attractive, noninvasive, and inexpensive tool. The present study aimed to evaluate the usefulness and reliability of IMD for guiding clip placement in aneurysm surgery.

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