The antitumor effect of mycelia extract of the medicinal macrofungus Inonotus hispidus on HeLa cells via the mitochondrial-mediated pathway.

Ethnopharmacological Relevance: Inonotus hispidus (I. hispidus), known as shaggy bracket, has been used extensively in China and some East Asian countries as a traditional medicinal macrofungus to treat difficult diseases, such as diabetes, gout, and arthritis. Modern pharmacological research has shown that I.

Soil microbial diversity and functional capacity associated with the production of edible mushroom in croplands.

In recent years, a rare edible mushroom has become popular. has the characteristics of easy cultivation, low cost, high output value, and low labor requirement, making its economic benefits significantly superior to those of other planting industries. Accumulating research demonstrates that cultivating edible fungus is advantageous for farming soil.

Whole-genome assembly and analysis of a medicinal fungus: .

() is a medicinal macrofungus that plays a key role in anti-tumor and antioxidant functions. To further understand and enhance the value of , we performed whole-genome sequencing and an analysis of its strain for the first time. was sequenced using the Illumina NovaSeq high-throughput sequencing platform.

HBx protein induces expression of MIG and increases migration of leukocytes through activation of NF-kappaB.

Elevated expression of monokine induced by the interferon-gamma (MIG) has been shown in HBV carriers, and it is involved in the infiltration of inflammatory cells and liver damage after HBV infection. However, the molecular mechanisms by which HBV-induced MIG expression have not been characterized. Our results indicated that HBx protein induced MIG expression in a dose-dependent manner.