Bioactive Earthworm Peptides Produced by Novel Protease-Producing PM 35 and Its Bioactivities on Liver Cancer Cell Death Apoptosis, Antioxidant Activity, Protection Against Oxidative Stress, and Immune Cell Activation.

Earthworms have long been used as traditional medicine. The purposes of this research were to create bioactive peptides from the unique earthworm (PAAEs) and test their potentials on liver cancer bioprophylactic activity, antioxidant, oxidative stress protection, and immune cell activation. This earthworm had a high protein content ratio, at 55.