Synopsis of recent research by authors named "Pilong Li"
- Pilong Li's recent research focuses on the mechanisms of liquid-liquid phase separation (LLPS) and its implications for gene regulation and therapeutic strategies in various biological contexts, including cancer and plant biology
- A significant finding is the role of JMJD1C in acute myeloid leukemia (AML), where it facilitates RUNX1-dependent gene expression, highlighting its potential as a therapeutic target across different genetic backgrounds of AML cells
- The studies also explore the impact of post-translational modifications, such as arginine methylation, on the assembly of ribonucleoprotein complexes, demonstrating their influence on neuronal granule formation and chromocenter dynamics in plants, suggesting a broad relevance of condensate biology in health and disease
