Context: DNA methylation in the diagnosis of gestational diabetes.
Objective: To assess the value of DNA methylation in the diagnosis of gestational diabetes (GDM) and in the prediction of maternal postpartum glucose disturbances.
Methods: Two-stage observational study performed between July 2006 and December 2010, at University Hospital.
Background/objectives: To study whether FGF21 was present in cord blood and explore its relationship with maternal variables and postnatal growth.
Subjects And Methods: The study included 157 pregnant women at the beginning of the third trimester; 79 with gestational diabetes (GDM), 78 with normal glucose tolerance (NGT), and their offspring. Glucose metabolism was assessed by oral glucose tolerance test.