Publications by authors named "Pil-Yun Kim"

Article Synopsis
  • - The study investigates a new hybrid scaffold for bone regeneration made from gellan gum, hydroxyapatite, and polyethylene glycol, enhanced with a compound from ginseng (CK) for better cell adhesion and growth.
  • - Scanning electron microscopy (SEM) showed that the scaffold had an ideal pore distribution for cell growth, and the inclusion of CK improved its biological activity, as determined by MTT assay results.
  • - Overall, the research suggests that this engineered scaffold can better resemble natural bone tissue, which may lead to advancements in bone regeneration therapies.
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Cartilage defects can be difficult to heal, potentially leading to complications such as osteoarthritis. Recently, a tissue engineering approach that uses scaffolds and growth factors has been proposed to regenerate new cartilage tissues. Herein, we investigated the application of hyaluronic acid (HA) gel loaded with transforming growth factor-beta 3 (TGF-β3) for enhanced cartilage regeneration.

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Hydrogels have shown to be advantageous in supporting damaged cartilage because of its analogous to the extracellular matrix (ECM) of cartilage tissue. However, problems such as infection and inflammation are still a challenge to be solved. In terms of tissue engineering, natural materials are more advantageous than synthetic materials in biocompatibility and biodegradability status.

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