Publications by authors named "Pigeaud L"
Background And Aims: Refractory celiac disease type II (RCDII) is characterized by a clonally expanded aberrant cell population in the small intestine. The role of other tissue-resident immune subsets in RCDII is unknown. Here, we characterized CD8 and CD4 T cells in RCDII duodenum at the single-cell level and .
View Article and Find Full Text PDFUnlabelled: Alcohol-related emergency department attendance in adolescents should be considered as a valuable opportunity to address and mitigate future alcohol consumption. Therefore, a paediatric department of a major district hospital in the Netherlands developed an outpatient preventive program targeting adolescents admitted for acute alcohol intoxication. The primary aim of this study is to evaluate how adolescent drinking patterns participating in the preventive program developed over time.
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- This study investigates how acute alcohol intoxication impacts creatinine kinase levels in adolescents under 18, using data from a Dutch hospital from 2008 to 2021.
- Out of 495 adolescents treated for alcohol intoxication, 60% had elevated creatinine kinase levels, and 4.4% were diagnosed with rhabdomyolysis.
- The findings indicate that higher blood alcohol concentrations correlate with increased creatinine kinase levels, highlighting the need for awareness regarding alcohol's effects on muscle tissue in young individuals.
Article Synopsis
- The study investigates how the COVID-19 lockdown affected acute alcohol intoxication rates among adolescents in the Netherlands, following earlier findings in Italy.
- A retrospective cohort study included adolescents under 18 admitted for intoxication in 12 hospitals, analyzing times before, during, and after the first lockdown compared to 2019.
- Results showed a 70% decrease in intoxication during the first lockdown, likely due to closures and increased parental supervision, but levels rose significantly during the reopening phase, highlighting the need for ongoing monitoring of adolescents.