Propentofylline reduces glial scar development following gliotoxic damage in the rat brainstem.

Objective: This study aimed to evaluate the effect of propentofylline administration on astrocytic response following gliotoxic injury.

Method: Wistar rats were injected with ethidium bromide into the cisterna pontis and treated or not with propentofylline (12.5mg/kg/day, intraperitoneal) during the experimental period.