Publications by authors named "Pietro Antonio Livio"

Article Synopsis
  • The introduction of biological drugs for treating cancers and autoimmune diseases has changed the medical landscape, but anti-drug antibodies (ADAs) can reduce their effectiveness.
  • Researchers developed an ambipolar electrolyte-gated transistor (EGT) immunosensor using reduced graphene oxide to detect low concentrations of ADAs specifically against Infliximab (IFX).
  • This new sensor is easy to make, operates at low voltages, delivers quick results, and can accurately measure ADAs even when competing with natural antagonists like TNF-α.
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During the last fifteen years, the reduction of electrically insulating graphene oxide (GO) through the elimination of oxygen containing functional groups and the restoration of sp conjugation yielding its conducting form, known as reduced graphene oxide (rGO), has been widely investigated as a scalable and low-cost method to produce materials featuring graphene-like characteristics. Among various protocols, thermal annealing represents an attractive green approach compatible with industrial processes. However, the high temperatures typically required to accomplish this process are energetically demanding and are incompatible with the use of plastic substrates often desired for flexible electronics applications.

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Health monitoring is experiencing a radical shift from clinic-based to point-of-care and wearable technologies, and a variety of nanomaterials and transducers have been employed for this purpose. 2D materials (2DMs) hold enormous potential for novel electronics, yet they struggle to meet the requirements of wearable technologies. Here, aiming to foster the development of 2DM-based wearable technologies, reduced graphene oxide (rGO)-based liquid-gated transistors (LGTs) for cation sensing in artificial sweat endowed with distinguished performance and great potential for scalable manufacturing is reported.

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