Investigation of myocardial bioimpedance at multiple frequencies for cardiac radiofrequency ablation: ex-vivo experiments.

Background: Bioimpedance method is used clinically as a surrogate measure of effective tissue heating during cardiac ablation. It does not, however provide information regarding thermal cellular destruction which is the goal of ablation procedures.

Objective: This study investigated myocardial impedance (resistance and reactance) at different frequencies in response to the thermal effect and across temperatures where tissue necrosis occurs during ablation.