Publications by authors named "Pierre P J G M de Wit"
Article Synopsis
- Understanding how pathogens like Zymoseptoria tritici defend against host-generated hydrogen peroxide (HO) is key to studying fungal infections.
- Our research focused on two catalase-peroxidase (CP) genes, ZtCpx1 and ZtCpx2, which help the fungus manage oxidative stress during infection.
- We found that ZtCpx1 is critical for the fungus's virulence and response to HO, while ZtCpx2 plays a supportive role; both genes together enhance the pathogen's ability to thrive in hostile environments.
Fungal plant pathogens, such as Zymoseptoria tritici (formerly known as Mycosphaerella graminicola), secrete repertoires of effectors to facilitate infection or trigger host defence mechanisms. The discovery and functional characterization of effectors provides valuable knowledge that can contribute to the design of new and effective disease management strategies. Here, we combined bioinformatics approaches with expression profiling during pathogenesis to identify candidate effectors of Z.
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