Publications by authors named "Pierre O Sellier"
The incidence of pulmonary embolism (PE) is high during severe Coronavirus Disease 2019 (COVID-19). We aimed to identify predictive and prognostic factors of PE in non-ICU hospitalized COVID-19 patients. In the retrospective multicenter observational CLOTVID cohort, we enrolled patients with confirmed RT-PCR COVID-19 who were hospitalized in a medicine ward and also underwent a CT pulmonary angiography for a PE suspicion.
View Article and Find Full Text PDFBackground & Aims: Hepatitis B Virus (HBV) DNA during chronic infection can reach levels at which mother-to-child (MTC) transmission frequently occurs despite passive-active immunization of newborns. Hepatitis D Virus (HDV) RNA can reach high levels, we assessed HBV/HDV MTC co-transmission.
Methods: Monocentric retrospective study (registered in ClinicalTrials.
Background: The risk of vertical transmission of hepatitis B virus (HBV) increases as maternal HBV DNA increase, despite serovaccination to newborns.
Methods: From 1 July 2012 to 1 January 2016, all pregnant women in Lariboisiere Hospital, Paris, France, with HBV DNA of 5 log10 IU/ml and above were administered tenofovir from week 28 of pregnancy until delivery. HBV DNA was measured at months 1, 2 of tenofovir and at delivery.
Article Synopsis
- The study evaluated the hepatitis B virus (HBV) status of children born to women who were coinfected with HIV and HBV, focusing on those who had access to antiretroviral therapy from 2000 to 2012.
- Out of 35 children studied, 74% developed protective antibodies against HBV after receiving HBV immunoglobulin and vaccines, indicating that maternal treatment with lamivudine or tenofovir/emtricitabine during pregnancy was effective.
- No child showed signs of chronic HBV infection, but there were instances of incomplete vaccination and uncertainty about immunoglobulin receipt, underscoring the need for larger studies to assess long-term vaccine protection.