Publications by authors named "Pierre Menager"

Article Synopsis
  • The COVIT-TRIAL study tested whether a high dose of vitamin D3 given within 72 hours of COVID-19 diagnosis improves 14-day survival rates in at-risk older adults compared to a standard dose.
  • Conducted in France across nine medical centers, the trial included patients aged 65 and older with confirmed SARS-CoV-2 infection and specific health risks.
  • Of the 1,207 patients evaluated, 254 were eligible and enrolled in the study, which aimed to measure overall mortality as the primary outcome.
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Background: Vitamin K concentrations are inversely associated with the clinical severity of COVID-19. The objective of this cohort study was to determine whether the regular use of vitamin K antagonist (VKA) prior to COVID-19 was associated with short-term mortality in frail older adults hospitalized for COVID-19.

Methods: Eighty-two patients consecutively hospitalized for COVID-19 in a geriatric acute care unit were included.

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Objectives: The use of vitamin K antagonists (VKA) is associated with the onset of vascular and soft-tissue calcifications. Whether there are more intracranial calcifications under VKA remains unclear. The objective of this study was to determine whether the regular use of VKA in older adults was associated with an increased burden of intracranial calcifications compared with the use of direct oral anticoagulant (DOA).

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