Evaluating the cost-consequence of a standardized strategy for the etiological diagnosis of uveitis (ULISSE study).

Main Objective: To prospectively assess the cost-consequence of a standardized diagnostic strategy as to compared to an open one for the etiological diagnosis of uveitis.

Design: This was a prospective, non-inferiority, multicentre, randomized controlled trial.

Methods: We included all consecutive patients with uveitis who had visited at least one of the Departments of Ophthalmology.

Contribution of diagnostic tests for the etiological assessment of uveitis, data from the ULISSE study (Uveitis: Clinical and medicoeconomic evaluation of a standardized strategy of the etiological diagnosis).

Purpose: ULISSE is the only study that prospectively assessed the efficiency of a standardized strategy, compared to an open strategy for the etiologic diagnosis of uveitis. Our aim was to evaluate the diagnostic yield of the tests prescribed in the ULISSE study to clarify their relevance.

Methods: ULISSE is a non-inferiority, prospective, multicenter and cluster randomized study.

Lithium-induced downbeat nystagmus.

We report the case of a 76-year old lady under lithium carbonate for a bipolar disorder who presented with a suspected optic neuritis. A typical lithium-induced downbeat nystagmus was observed. Discontinuation of lithium therapy resulted in frank improvement in visual acuity and disappearance of the nystagmus.

Randomized Controlled Trial Evaluating a Standardized Strategy for Uveitis Etiologic Diagnosis (ULISSE).

Purpose: To prospectively assess the efficiency of a standardized diagnostic approach, compared to an open strategy, for the etiologic diagnosis of uveitis.

Design: Noninferiority, prospective, multicenter, clustered randomized controlled trial.

Methods: Consecutive patients with uveitis, who visited 1 of the participating departments of ophthalmology, were included.

Corneal endothelium self-healing mathematical model after inadvertent descemetorhexis.

Unlabelled: An 85-year-old man presented with an unusual complication of cataract surgery. During injection of an ophthalmic viscosurgical device, Descemet membrane was accidentally dissected and removed during the capsulorhexis. Early postoperative visual acuity was counting fingers as a result of massive corneal edema.

In vivo confocal microscopy of pine processionary caterpillar hair-induced keratitis.

Purpose: Multimodal imaging of processionary caterpillar hair-induced keratitis with anterior segment optical coherence tomography and in vivo confocal microscopy.

Methods: Case report.

Results: A 25-year-old woman presented with acute keratitis induced by multiple tiny processionary caterpillar hairs.

No loss of chance of diabetic retinopathy screening by endocrinologists with a digital fundus camera.

Objective: To compare the efficacy of the diabetic retinopathy (DR) screening with digital camera by endocrinologists with that by specialist and resident ophthalmologists in terms of sensitivity, specificity, and level of "loss of chance."

Research Design And Methods: In a cross-sectional study, 500 adult diabetic patients (1,000 eyes) underwent three-field retinal photography with a digital fundus camera following pupillary dilatation. Five endocrinologists and two ophthalmology residents underwent 40 h of training on screening and grading of DR and detection of associated retinal findings.

Screening for diabetic retinopathy by ophthalmologists and endocrinologists with pupillary dilation and a nonmydriatic digital camera.

Purpose: To assess the effects of pupillary dilation on image quality and certitude of screening diabetic retinopathy by trained endocrinologists using a digital nonmydriatic camera.

Design: Prospective, comparative, observational case series.

Methods: One hundred fifty patients with diabetes attending a hospital-based photographic screening clinic had five-field (45 degree) digital retinal imaging and mosaic construction, first through dark-adapted pupils, then after a single application of tropicamide 1%.