Publications by authors named "Pierre Lespinasse"
Article Synopsis
- Brenner tumors are types of ovarian epithelial tumors that can present as benign, borderline, or malignant, and the case discussed highlights one associated with postmenopausal bleeding and elevated estradiol levels.
- A 59-year-old woman, who had been menopausal for seven years, experienced postmenopausal bleeding and underwent various evaluations, including ultrasound and biopsies, leading to findings of a mass in the right adnexa.
- Ultimately, the patient had a laparoscopic hysterectomy which revealed the mass to be a Brenner tumor; the case emphasizes the importance of evaluating persistent postmenopausal bleeding to rule out serious conditions like endometrial cancer.
Does Living With Human Immunodeficiency Virus Increase Pelvic Reconstructive Surgery Perioperative Complication Risk? A Multicenter Retrospective Cohort Study.
Female Pelvic Med Reconstr Surg
July 2020
Objective: To determine if women with human immunodeficiency virus (HIV) undergoing pelvic reconstructive surgery (PRS) have an increased risk of perioperative and postoperative complications compared with HIV-negative controls.
Study Design: Multicenter, retrospective matched cohort study of patients with and without HIV infection who underwent PRS between 2006 and 2016. Cases were identified using International Classification of Disease, 9th edition Clinical Modification and 10th edition Clinical Modification and current procedural terminology (CPT) codes encompassing HIV diagnoses and pelvic reconstructive surgeries.
Interferonε (IFNε) is a unique type I IFN that has distinct functions from IFNα/β. IFNε is constitutively expressed at mucosal tissues, including the female genital mucosa, and is reported to be modulated by estrogen and seminal plasma. However, its regulation by cytokines, including TNFα, IL-1β, IL-6, IL-8, IL-17, IL-22 and IFNα, which are commonly present in the female genital mucosa, is not well documented in freshly isolated primary cervical cells from tissues.
View Article and Find Full Text PDFBackground: CD4 T cells are crucial for the establishment and dissemination of HIV in mucosal tissues during acute infection. Studies indicate that integrin α4β7 CD4 T cells are preferentially infected by HIV in vitro and during acute SIV infection. The integrin α4β7 is thought to promote HIV capture by target cells; however, the role of integrin α4β7 in HIV transmission remains controversial.
View Article and Find Full Text PDFVesicouterine fistula is a rare complication that may occur after multiple cesarean deliveries. The following reports describe cases where vesicouterine fistula was misdiagnosed; one was initially treated for urge incontinence, and the other was treated for stress urinary incontinence.
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