Publications by authors named "Pierre Lauroua"
Background: Childhood autoimmune hemolytic anemia (AIHA) is a rare and severe disease characterized by hemolysis and positive direct antiglobulin test (DAT). Few epidemiologic indicators are available for the pediatric population. The objective of our study was to reliably estimate the number of AIHA cases in the French Aquitaine region and the incidence of AIHA in patients under 18 years old.
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- Parenteral artesunate is the recommended first-line treatment for severe malaria, but concerns about its long-term safety are emerging, particularly regarding delayed haemolytic anaemia in patients after treatment.* -
- This case report details a 17-year-old Ivoirian girl who developed autoimmune haemolytic anaemia following treatment for severe malaria with parenteral artesunate, despite initial improvement in her condition.* -
- The patient’s blood tests showed signs of hemolysis and a positive Coombs' test for drug-induced antibodies related to artesunate, leading to the conclusion that the anaemia was likely drug-mediated, and she was subsequently treated with corticosteroids.*
Background: RH1 is one of the most clinically important blood group antigens in the field of transfusion and prevention of fetomaternal incompatibilities. New variant RHD alleles are regularly identified and their characterization is essential to ensuring patient safety.
Study Design And Methods: Blood samples with uncertain RhD phenotypes not resolved by our first-line SNaPshot assay were sequenced for all 10 RHD exons.
Background: D(C)(e) and D(C)e haplotypes may be encountered in the white population. Few data are available on the molecular backgrounds responsible for depressed expression of C and e.
Study Design And Methods: Individuals of white origin carrying a D(C)(e) genotype resulting in depressed expression of C or both C and e were subdivided into two categories based on the RBC reactivity with the human sera Mol and Hor, which contain antibodies against low-frequency antigens of the Rh (RH) system and other non-Rh low-frequency antigens.