A finite element model of the embryonic zebrafish heart electrophysiology.

Background And Objective: In the last 30 years, a growing interest has involved the study of zebrafish thanks to its physiological characteristics similar to those of humans. The aim of the following work is to create an electrophysiological computational model of the zebrafish heart and lay the foundation for the development of an in-silico model of the zebrafish heart that will allow to study the correlation between pathologies and drug administration with the main electrophysiological parameters as the ECG signal.

Methods: The model considers a whole body and the two chambers of three days post fertilization (3 dpf) zebrafish.