Publications by authors named "Pierre Hernandez"
Article Synopsis
- Most HIV rapid tests primarily detect antibodies, which makes them less effective in identifying early HIV infections.
- The Determine test, which includes p24-antigen detection, shows better overall sensitivity compared to the One-Step test, particularly during the early stages of infection.
- Using tests that detect p24-antigen can reduce the diagnostic window significantly, from around 3 months to about 1 month, but caution is advised when testing in the first month after infection.
Article Synopsis
- The study compares the effectiveness of two serological screening tests, Alinity i rHTLV-I/II and LIAISON® XL murex recHTLV-I/II, against the ARCHITECT rHTLVI/II test for diagnosing HTLV-I and II infections.
- It involved analyzing 119 serum samples from known HTLV-I patients and 184 from uninfected individuals to evaluate the tests' performance.
- Results showed that both Alinity i and LIAISON® tests had total agreement with the ARCHITECT reference test, making them reliable options for HTLV screening.
In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modifications on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property.
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