Experimental study of a late response recorded from the thoracic wall after phrenic nerve stimulation.

Objectives: The phrenic nerve cervical stimulation induces an early motor diaphragmatic M response that may be recorded from the 7th ipsilateral intercostal space (ICS). Some responses with prolonged latency and of unclear origin can be recorded from the same recording site. The aim of the study was to determine the electrophysiological characteristics and the neuroanatomical pathways underlying the long-latency responses (LLRs) recorded from the 7th ICS.

A new MPZ mutation associated with a mild CMT1 phenotype presenting with recurrent nerve compression.

P0 is a transmembrane protein of the immunoglobulin superfamily that plays a role in myelin structure and function. Myelin protein zero gene (MPZ) mutations usually cause a demyelinating variant of Charcot-Marie-Tooth disease type 1B (CMT1B), but there is a wide spectrum of phenotypic manifestation of these mutations. We describe three patients from one family and one separate patient who presented with a demyelinating neuropathy.

Electrophysiological recording of deep tendon reflexes: normative data in children and in adults.

Objective: Latency measurement of myoelectric deep tendon (T) reflex responses is not usually performed in EMG laboratories. We investigated the optimal conditions of reliable recording of T reflex in children and adults.

Methods: Two hundred and sixty-eight normal subjects (139 males, 129 females, age rank 2 days-80 years) were studied.