Publications by authors named "Pierre Claver Oundoum Oundoum"
Evaluation of the toxicity of Colocasia esculenta (Aracaceae): Preliminary study of leaves infected by Phytophthora colocasiae on wistar albinos rats.
Doriane Camille Nyonseu Nzebang Marie Ide Ngaha Njila Emma Fortune Bend Pierre Claver Oundoum Oundoum Brice Landry Koloko
Biomed Pharmacother
March 2018
Article Synopsis
- The study examined the toxicity of aqueous extracts from Colocasia esculenta leaves infected by Phytophthora colocsiae in Wistar rats, assessing both acute and subacute effects.
- Acute administration of doses up to 4000 mg/kg showed no immediate toxicity signs or mortality, suggesting a high LD50, while subacute treatment at 800 mg/kg in males led to symptoms like spiky hair, breathing issues, and death.
- Significant changes in blood parameters and adverse effects on lung tissues were observed, indicating potential health risks at higher or repeated doses of the infected extract.