Fermentation of coffee fruit with sequential inoculation of Lactiplantibacillus plantarum and Saccharomyces cerevisiae: effect on sensory attributes and chemical composition of the beans.

This study has innovative aspects related to the use of sequential inoculation technique in the coffee bean fermentation process: the inoculation of Lactiplantibacillus plantarum followed by Saccharomyces cerevisiae, in the fermentation of coffee fruit for the production of specialty natural coffees. The objective was to evaluate the effect of this technique and of the total fermentation time on the sensory attributes of the coffee beverage and on the organic acid profile, bioactive compounds, and fatty acid profile of the beans. The fermentation of coffee fruit with sequential inoculation resulted in greater acidity of the beverage and contributed to increases of up to 2 points in coffee fermented.

Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin.

We describe the case of a patient in whom anticonvulsant hypersensitivity syndrome developed during treatment with phenytoin and progressed when therapy was changed to phenobarbital. Although therapeutic options remain controversial, corticosteroids and IV immunoglobulin were used in our patient. The patient had a complete recovery, suggesting the potential benefit of corticosteroids and IV immunoglobulin for anticonvulsant hypersensitivity syndrome.

Acute effects of thirty minutes of light-intensity, intermittent exercise on patients with chronic fatigue syndrome.

Background And Purpose: Currently, there is no consensus on exercise prescription for patients with chronic fatigue syndrome (CFS). This investigation examined whether light-intensity, intermittent physical activity exacerbated symptoms in patients with CFS immediately following exercise to 7 days following exercise. Subjects.

Acute respiratory distress syndrome: a clinical update.

Background: Because of recent advances in the treatment and improved outcome of acute respiratory distress syndrome (ARDS), we present an overview of ARDS to update general practitioners on the management of this condition.

Methods And Results: We searched MEDLINE for original articles, editorials, and reviews on ARDS, acute lung injury, and mechanical ventilation. A large amount of data is available on this subject.

Normal versus pathological aging: knowledge of family practice residents.

Family physicians may lack discriminatory ability to differentiate normal aging from disease states. To assess such ability, 53 aging-related indicators or symptoms were presented to 65 physicians in three family practice residency programs. Respondents classified each symptom as normal aging or disease.

Preventing falls in hospitals. The roles of patient age and diagnostic status in predicting falls.

Patient falls are some of the most frequent accidents in hospitals, and they can lead to significant personal and financial costs for both patients and facilities. This study examines the relationship between two patients characteristics and patient falls at a large general hospital and a small psychiatric facility in Tennessee; its findings should be useful for hospital risk management.

Limitations to heavy work at 21 degrees C of personnel wearing the U.S. military chemical defense ensemble.

The purpose of this study was to determine the limitations to work of personnel performing heavy work at 21 degrees C (70 degrees F) while wearing the chemical defense ensemble (CDE) worn by all branches of the U.S. military.

Severe hypoglycemia associated with trimethoprim-sulfamethoxazole therapy.

Hypoglycemia associated with sulfamethoxazole therapy in patients with chronic renal insufficiency has previously been documented. We report the case of an elderly patient with relatively normal renal function who developed severe hypoglycemia associated with trimethoprim-sulfamethoxazole therapy.

Rubeola.

Although immunization practices have dramatically reduced the incidence of measles, several populations remain at risk of the disease. Modified measles may occur in those who received immune globulin in childhood. Atypical measles, often confused with Rocky Mountain spotted fever, may develop in those who received inactivated measles virus vaccine and were subsequently exposed to the natural disease.

Fatal digoxin-quinidine interaction in an elderly woman.

The medical records of an elderly woman revealed strong evidence of a lethal digoxin-quinidine interaction. This case and several problems contributing to digitalis toxicity are presented. Physicians should be more aware of the potential toxicities involved in cardioactive drug therapy in the elderly.

Radioimmunoassayable serum somatomedin B in normal subjects and in patients with acromegaly and pituitary dwarfism: effects of human growth hormone therapy.

We report the results obtained with a radioimmunoassay for serum somatomedin B (SmB) in 29 normal subjects, in 33 pituitary dwarfs (GHD) and 6 acromegalic patients. There were no significant differences between the basal SmB levels of the GHD and the normal subjects higher value observed in the acromegalic group (p < 0.01).

Tetanus and diphtheria immune status of patients in a family practice.

Sera obtained randomly from 37 patients seen at a family practice center were evaluated for protective antibodies against tetanus and diphtheria using in vivo toxin neutralization methods. The patients' ages ranged from 1 to 99 years. Seventy-four percent and 83 percent of patients were found to have protective antitoxin titers against tetanus and diphtheria, respectively.