Publications by authors named "Pienkowska J"

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  • This study aimed to evaluate the added value of hepatobiliary phase (HBP) contrast agents in diagnosing hepatocellular carcinoma (HCC) by reviewing existing meta-analyses since 2010.
  • Data from 13 studies, which included a total of 1184 HCC lesions, were analyzed to compare diagnostic performance metrics (sensitivity and specificity) between methods using HBP and those without it.
  • Results showed that while both methods were effective, there was no statistically significant difference in sensitivity between the two approaches, indicating that HBP may not enhance HCC diagnosis as previously thought.
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Features of shell and genitalia as well as nucleotide sequences of selected mitochondrial and nuclear genes of specimens of from ten northern French and two Dutch populations were compared with the same features of British and Italian populations. They were found to be very similar to populations previously identified as belonging to the CAN-1 lineage of . This confirms previous suggestions that was introduced to western Europe (England, France and the Netherlands) in historical times.

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  • The study looked at how to tell the difference between benign (non-cancerous) and malignant (cancerous) liver lesions using a special MRI with a substance called gadoxetic acid.
  • Researchers examined 107 patients with 180 liver lesions, analyzing both benign and malignant types.
  • They discovered that there were significant differences in the measurements taken from these lesions, which could help doctors determine if a lesion is cancerous or not.
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  • The study evaluated the effectiveness of core biopsy for diagnosing pancreatic cancer, focusing on its sensitivity, accuracy, and safety.
  • In a group of 100 patients, core biopsy showed a sensitivity of 92%, specificity of 100%, and an accuracy of 93.3%, with only 1% experiencing serious complications.
  • The findings suggest that core biopsy may be more effective and cost-efficient than the commonly used endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for obtaining tissue samples.
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COVID-19 infection is associated with myocarditis, and cardiovascular magnetic resonance (CMR) is the reference non-invasive imaging modality for myocardial tissue characterization. Quantitative CMR techniques, such as feature tracking (FT) and left ventricular global longitudinal strain (GLS) analysis, have been introduced as promising diagnostic tools to improve the diagnostic accuracy of suspected myocarditis. The aim of this study was to analyze the left ventricular global longitudinal strain (GLS) and the influence of T1 and T2 relaxation times, ECV, and LGE appearance on GLS parameters in a multiparametric imaging protocol in patients who recovered from COVID-19.

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The mitochondrial genome of is the first complete mitochondrial sequence described for the pulmonate snail genus and for the family Hygromiidae. The identified mitogenome has a length of 13,894 bp and encodes 13 proteins, 22 tRNAs, and two rRNAs. A phylogenetic analysis of available mitogenomes from representatives of helicoid families shows a sister group relationship of Hygromiidae and Geomitridae, which have been recently recognised as separate families.

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Introduction: We hypothesized that, based on magnetic resonance enterography (MRE) and the apparent diffusion coefficient (ADC), measured in the affected parts of the intestine, it is possible to effectively differentiate active and chronic phases of Crohn's disease.

Aim: To create a multidimensional diagnostic model for differentiating between the phases of Crohn's disease.

Material And Methods: This study included 125 patients - 55 women (aged 19 to 66 years) and 70 men (aged 12 to 67 years) - who underwent MRE and ADC measurement for the first time.

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Irreversible electroporation (IRE) of locally advanced pancreatic cancer is an increasingly used method for unresectable pancreatic cancer that can be used in cytoreduction followed by surgical treatment and shows promising results in palliative care. IRE is an ablative technique where electric pulses cause damage to the cell membrane leading to apoptosis without the destruction of stroma. The application of IRE increases the concentration of hydrophobic regimens like bleomycin within the tumor, what could improve the effectiveness of treatment.

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The construction of an engine requires optimized geometry and superb material properties in various environments. Tensile and yield strength are not the only parameters essential to consider. Hardness, impact toughness, and ductile-brittle transition temperature (DBTT) are also crucial.

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Specimens obtained from ten populations of a species from the central Apennines were compared with six molecular lineages of s. l. (CAN-1, CAN-2, CAN-3, CAN-4, CAN-5, CAN-6) and two other species ( and ), treated as outgroup, by molecular (nucleotide sequences of two mitochondrial COI and 16S rDNA as well as two nuclear ITS2 and H3 gene fragments) and morphological (shell and genital anatomy) analysis.

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Background: Radiological imaging methods used at a large scale in the assessment of hepatic lesions include: Ultrasound, computed tomography and magnetic resonance. To further characterize these lesions, specific contrast agents may be added, thus revealing the vascularity of the lesions.

Discussion: This review focuses on gadoxetic acid, which is a hepatospecific contrast agent used in MRI.

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The widespread presence of overweight and obesity increases with every decade, and the number of people with body mass index (BMI) >30 kg/m2 has doubled in the last 30 years. The aim of the study is to assess the correlation between MRI-evaluated ectopic fat accumulation in pancreas, skeletal muscles and liver and the incidence of type 2 diabetes and hypertension, depending on BMI and waist circumference ratio. This prospective study included 267 consecutive patients who were referred to abdominal MRI and underwent a standard clinical assessment with BMI and waist circumference ratio calculation.

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Autosomal dominant polycystic kidney disease (ADPKD) constitutes the fourth cause of end-stage renal disease in Europe. The course of the disease varies widely among patients with ADPKD. Due to the emergence of new possibilities of pharmacotherapy, it has become crucial to identify the group of patients with the fastest rate and risk of disease progression.

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  • The study aimed to determine the effectiveness of liver perfusion parameters measured by CT in predicting the severity of acute pancreatitis (AP) in patients during their first day of symptoms.
  • 79 patients with AP were analyzed using perfusion CT, comparing those who developed severe AP (41 patients) to those with mild cases (38 patients).
  • Results showed significant differences in liver perfusion, with severe AP patients having lower permeability-surface area and higher hepatic arterial fraction, indicating that p-CT may help identify patients at higher risk for severe AP.
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Obesity, defined as a body mass index (BMI) exceeding 30 kg/m, is a serious health problem, which can be called an epidemic on a global scale and is one of the most important causes of preventable death. The aim of this study was to assess ectopic fat accumulation in pancreas, liver and skeletal muscle in patients with obesity, overweight and normal BMI in correlation with metabolic syndrome (MetS). The study included 267 consecutive patients who underwent a standard clinical assessment with BMI calculation.

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Two new lineages CAN-5 and CAN-6 were recognised in four populations of (Montagu, 1803) s.l. from the Italian Apuan Alps by joint molecular and morphological analysis.

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Molecular analysis of nucleotide sequences of mitochondrial cytochrome oxidase subunit 1 (COI) and 16S ribosomal DNA (16SrDNA) as well as nuclear histone 3 (H3) and internal transcribed spacer 2 of rDNA (ITS2) gene fragments together with morphological analysis of shell and genitalia features showed that English, French and Italian populations usually assigned to consist of four distinct lineages (CAN-1, CAN-2, CAN-3, CAN-4). One of these lineages (CAN-1) included most of the UK (five sites) and Italian (five sites) populations examined. Three other lineages represented populations from two sites in northern Italy (CAN-2), three sites in northern Italy and Austria (CAN-3), and two sites in south-eastern France (CAN-4).

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  • Neurosyphilis is linked to central nervous system vasculitis that affects medium and small blood vessels, causing disruptions in white matter due to water molecule diffusion changes.
  • A study of MRI images from two neurosyphilis patients showed increased apparent diffusion coefficient (ADC) values in their white matter, despite it appearing normal.
  • Analyzing ADC values can uncover hidden brain changes in neurosyphilis patients and may relate to their neuropsychiatric symptoms, highlighting the severity of the disease's impact on the CNS.
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Clear-cell renal carcinoma constitutes over 90% of all cases of renal cancers. One of the least common locations of metastases of this type of cancer are skeletal muscles. We believe that this is the first case ever presented of renal clear-cell cancer metastasis to the extensor digitorum muscle.

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Water channel proteins, classified as a family of Membrane Intrinsic Proteins (MIPs) superfamily, enable rapid movement of water and small uncharged molecules through biological membranes. Although water channel proteins are required in several important processes characteristic for the animals, such as osmoregulation, mucus secretion, or defense against desiccation, molluscs, until now, have been very poorly explored in this aspect. Therefore, we decided to study MIPs in Helix pomatia L.

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