Weight gain in menopause: systematic review of adverse events in women treated with black cohosh.

Weight gain is a frequent problem in perimenopausal and postmenopausal women. (CR) is a popular treatment option for menopausal symptoms. The aim of this review was to investigate whether there is scientific evidence that CR causes weight gain.

Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms - an update on the evidence.

A systematic literature search revealed 35 clinical studies and one meta-analysis comprising 43,759 women, of which 13,096 were treated with isopropanolic extract (iCR). Compared to placebo, iCR was significantly superior for treating neurovegetative and psychological menopausal symptoms, with a standardized mean difference of -0.694 in favor of iCR ( < 0.

Benefit-risk profile of black cohosh (isopropanolic extract) with and without St John's wort in breast cancer patients.

Endocrine therapy in breast cancer survivors can cause severe 'climacteric' symptoms, which may compromise therapy adherence. To determine whether such symptoms can be treated with herbal medication containing black cohosh in the form of isopropanolic extract (iCR) alone or in fixed combination with St John's wort ( [HP]) (iCR + HP), a systematic literature search was conducted. Results were viewed in relation to experimental data and metabolism of endocrine therapies.

Asymptotically stable compensation of the soliton self-frequency shift.

We report on the stable cancellation of the soliton self-frequency shift (SSFS) in nonlinear optical fibers. A soliton, which scatters a group velocity matched pump wave in a so-called optical event horizon regime, may experience a blueshift in frequency, which counteracts the SSFS induced by Raman scattering. The SSFS can easily be compensated by a suitably prepared pump wave, but usually the compensation is unstable and is destroyed after a certain propagation length.