Publications by authors named "Pichaporn Artornsombudh"
Purpose: To evaluate the incidence, remission, and relapse of post-surgical cystoid macular edema (PCME) following cataract surgery in inflammatory eye disease.
Methods: A total of 1859 eyes that had no visually significant macular edema prior to cataract surgery while under tertiary uveitis management were included. Standardized retrospective chart review was used to gather clinical data.
Article Synopsis
- The study aimed to analyze the relationship between immunosuppression and overall as well as cancer-specific mortality in patients with noninfectious ocular inflammatory disease.
- Researchers examined data from over 15,000 patients over a median of 10 years and found there were 1970 deaths, with 435 attributed to cancer.
- The results indicated that patients on various immunosuppressants experienced similar mortality rates compared to the general U.S. population, suggesting that these treatments did not significantly increase overall or cancer mortality risk.
Purpose: To estimate the incidence/risk factors for cataract in noninfectious anterior uveitis.
Design: Retrospective multicenter cohort study (6 US tertiary uveitis sites, 1978-2010).
Methods: Data were harvested by trained expert reviewers, using protocol-driven review of experts' charts.
Purpose: To evaluate the long-term visual acuity (VA) outcome of cataract surgery in inflammatory eye disease.
Setting: Tertiary care academic centres.
Design: Multicentre retrospective cohort study.
Article Synopsis
- The study aimed to estimate the incidence of corneal endothelial transplantation (CET) and identify risk factors in patients with noninfectious ocular inflammation using data from a cohort study of adult patients in the U.S.
- A total of 14,264 eyes were analyzed, revealing a 10-year incidence rate of 1.10% for CET, with notable risk factors including older age (over 60), specific types of inflammation (anterior uveitis and scleritis), and prior operations like cataract and tube shunt surgery.
- The findings suggest that while CET is rare among these patients, certain conditions like hypotony and band keratopathy significantly increase the likelihood of requiring the procedure.
: To demonstrate the reliability of conjunctival biopsy analyzed by direct immunofluorescence (DIF) and supplemented with avidin-biotin complex immunoperoxidase (ABC) in diagnosing oMMP, and report therapy response in biopsy-positive patients, particularly when previously biopsy-negative elsewhere.: Retrospective outcomes review of 136 consecutive patients after conjunctival biopsy for suspected oMMP.: Among 136 patients, 66% were diagnosed with oMMP by DIF and 13% via supplemental ABC immunoperoxidase.
View Article and Find Full Text PDFPurpose: To estimate the incidence of medication-free remission of chronic anterior uveitis and identify predictors thereof.
Design: Retrospective cohort study.
Participants: Patients diagnosed with anterior uveitis of longer than 3 months' duration followed up at United States tertiary uveitis care facilities.
Purpose: To compare mycophenolate mofetil (MMF) to methotrexate (MTX) as corticosteroid-sparing therapy for ocular inflammatory diseases.
Design: Retrospective analysis of cohort study data.
Methods: Participants were identified from the Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study.
Purpose: To evaluate adalimumab as an immunomodulatory treatment for non-infectious ocular inflammatory diseases.
Methods: Characteristics of patients treated with adalimumab were abstracted in a standardized chart review. Main outcomes measured were control of inflammation, corticosteroid-sparing effect, and visual acuity.
Purpose: To evaluate the risk of and risk factors for retinal neovascularization (NV) in cases of uveitis.
Design: Retrospective cohort study.
Participants: Patients with uveitis at 4 US academic ocular inflammation subspecialty practices.
Objective: To evaluate the demographic and clinical characteristics of patients referred to a tertiary care hospital cornea clinic for ocular cicatricial pemphigoid (OCP) assessment.
Design: Retrospective, nonrandomized, consecutive case series.
Participants: Thirty three patients with OCP who were treated at the corneal clinic of Toronto Western Hospital from 2003 to 2012.
Purpose: To evaluate the clinical features and outcomes of patients with recurrent corneal erosion syndrome who underwent anterior stromal puncture.
Study Design: Retrospective, nonrandomized, consecutive case series.
Methods: Database search of patients from 2003-2013 who underwent anterior stromal puncture was conducted at a tertiary care hospital cornea clinic.
Purpose: To identify factors predictive of remission of inflammation in new-onset anterior uveitis cases treated at tertiary uveitis care facilities.
Design: Retrospective cohort study.
Participants: Patients seeking treatment at participating academic uveitis clinics within 90 days of initial diagnosis of anterior uveitis.
Purpose: To evaluate the efficacy of bromfenac drops alone or with a single intravitreal injection of bevacizumab (IVB) or triamcinolone acetonide (IVTA) in the treatment of uveitic macular edema (UME).
Design: Comparative case series. STUDY PARTICIPANT: Sixty-seven eyes (of 55 patients) with UME that received either bromfenac drops alone (n = 34), IVB plus bromfenac (n = 21) or IVTA plus bromfenac (n = 12).
Purpose: To study the prevalence of conjunctival neoplasia in clinically diagnosed pterygia and the clinicopathologic characteristics of conjunctival tissues obtained from pterygium excision.
Design: Prospective, observational case series.
Participants: From February through August 2007, consecutive subjects indicated for pterygium excision were enrolled from an outpatient eye clinic of King Chulalongkorn Memorial Hospital, Bangkok, Thailand, and from the eye camp at the 6th Station of the Thai Red Cross Society, Aranyaprathet District, Sa Kaeo, Thailand.
Purpose: To report the outcomes of infliximab treatment of birdshot retinochoroidopathy (BSRC) refractory to conventional immunomodulatory therapy.
Design: Retrospective case series.
Participants: Twenty-two refractory birdshot retinochoroidopathy patients (44 eyes) who received infliximab between July 2005 and June 2012 were identified by retrospective chart review.