Publications by authors named "Piccolo Domenico"

The main categories of transition metal-mercury heterometallic compounds are briefly summarized. The attention is focused on complexes and clusters where the {Hg-Y} fragment, where Y represents a halide atom, interacts with transition metals. Most of the structurally characterized derivatives are organometallic compounds where the transition metals belong to the Groups 6, 8, 9 and 10.

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The body contour market has grown rapidly in recent years, due to persistent requests for noninvasive treatments for localized fat adiposities, cellulite, and skin laxity. A variety of different methods are now available to improve body shaping. This review aims to provide an exhaustive compendium of the main recommendations for the optimal use of an innovative device delivering microwaves (MWs) for unwanted fat and cellulite reduction (Onda Coolwaves, DEKA, Florence, Italy), resulting from the experiences of the most expert international users.

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Background: The market requires ever-faster techniques, in particular for pre-rejuvenation condition.

Aim: The purpose of this study was to assess if a fractional CO scanner modality (called moveo) results in a faster full-face rejuvenation treatment in comparison to the standard mode, currently existing in the scanner system.

Materials And Methods: A total of 12 female patients affected by fine lines participated in a split-face clinical investigation and underwent to two sessions with a fractional CO laser system equipped with an existing and a faster dedicated scanner units.

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Background: The options for treating pseudogynecomastia are limited, and there is a growing demand for noninvasive breast fat reduction. We evaluated the efficacy and safety of a laser-assisted lipolysis (LAL) device emitting 1444 nm for the treatment of pseudogynecomastia.

Methods: A total of 9 male patients diagnosed with pseudogynecomastia underwent laser procedure with a Nd:YAG laser emitting at 1444 nm.

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: Facial telangiectasias is a prevalent cosmetic disorder that can be associated with several conditions such as rosacea. IPL (intensity pulsed light) therapy is commonly used for the treatment of vascular lesions. This study tested the efficacy of an IPL system emitting selected vascular chromophore-specific wavelengths in the range of 500-1200 nm for the treatment of vascular lesions.

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Article Synopsis
  • * The study evaluated the safety and effectiveness of Q-switched 1064/532 nm lasers in treating benign hypermelanosis in 30 participants with darker skin (Fitzpatrick IV-V-VI), who underwent 1 to 2 laser sessions.
  • * Results showed 93% of patients experienced varying degrees of improvement in their skin pigmentation after three months, with no serious side effects reported, highlighting the laser's efficacy for darker skin types.
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Introduction: An excessive proliferation of fibroblasts and collagen synthesis after an injury may lead to a benign fibrous tumor, known as keloid, which does not regress spontaneously. Earlobes are a very frequent site of onset, since after a trauma (i.e.

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Background: Patients with keloids are often younger than 30 years old and have darker skin.

Aim: To evaluate the efficacy and safety of CO laser therapy in the management of earlobe and helix keloids in dark subjects.

Methods: A total of 21 dark patients (five men and 16 women) presented with the earlobe and ear helix keloids, with a mean age of 30.

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Alexandrite 755 nm laser has been currently recognized one of the gold standards for the permanent hair removal business because of its sufficient tissue penetration and higher affinity for melanin compared with Nd:YAG, making the treatment more incisive and effective. In this study, we evaluated an Alexandrite 755 nm laser with a 30-mm spot for a new and fast hair removal treatment. Patients of both genders, with skin Fitzpatrick's types, ranging from II to III, were asked to avoid any epilation techniques 4 weeks before the laser hair removal session.

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Dermal fillers for soft tissue for the treatment of face sagging, volume loss, and wrinkles have become popular among patients of all ages and ethnicities, and their use is becoming increasingly widespread. Aim: the goal of this study was to evaluate the effectiveness and safety of a micro-pulsed, 1444 nm Nd:YAG laser on dermal filler complications, in particular on granuloma management. A subcutaneous, 1444 nm Nd:YAG laser was used on five female patients (range age 52-68 years) with hyaluronic filler granulomas located on the face (two on the cheek area and three on the lips); three patients had self-injected the filler, buying it online.

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Background: The aging process starts in the center of the face, in the periocular region and around the mouth, with a combination of volume loss, tissue descent, deepened wrinkles, and the loss of skin structure and quality. Recently, several studies have demonstrated the efficacy of therapies based on autologous adipose tissue grafting, which leverages the properties of stromal vascular fraction (SVF) and adipose-derived mesenchymal stem cells (ADSCs) to accelerate the regenerative processes of the skin. This study aims to verify the ability of guided superficial enhanced fluid fat injection (SEFFI) in the facial area to correct volume loss and skin aging, proving that this standardized procedure has a very low rate of complications.

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Background: Body contouring is a significant area of dermatologic and plastic surgery. Surgical procedures, like surgical lipectomy, and less invasive procedures, such as various liposuction techniques, are the two main ways to reduce fat.

Aim: Our study showed that 1444 nm Nd:YAG laser-assisted lipolysis used with appropriate and specific parameters effectively destroys adipose tissue avoiding these risks and determining a safe clinical application.

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Article Synopsis
  • Photo/chrono-aging results in various facial issues like wrinkles, discoloration, and dehydration that negatively affect a person's quality of life.
  • A study treated 35 patients (mostly women) with a 675 nm laser for facial aging, showing significant improvement in wrinkles and some vascular improvements with minimal side effects.
  • The treatment proved effective, providing stable results over time while ensuring a comfortable experience for patients.
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Article Synopsis
  • - This study evaluates a new scanning system using a carbon dioxide (CO) laser for deeper skin resurfacing, aiming to enhance treatment for deep scarring.
  • - Laser treatment was conducted on male skin tissue, and the resulting microablation columns were observed to penetrate up to 6 mm deep into the dermis, indicating effective tissue injury at higher energy levels.
  • - The findings suggest that the CO laser system can effectively target both superficial and deep skin issues, potentially benefiting patients with severe scarring and improving their quality of life.
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The fourth most common healthy skin phenomenon is aging. To assess the efficacy of Nd:YAG laser with a new handpiece for the treatment of wrinkles and skin laxity. A total of 30 patients underwent three laser sessions at 1-month intervals.

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: A current popular aesthetic problem, especially among younger women, is striae distensae (SD), also referred to as "stretch marks.". : The potential use of the 675 nm laser has been investigated in the treatment of SD.

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Background: Blepharoplasty is one of the most popular esthetic procedures with an acceptable risk profile and a relatively quick procedure.

Methods: The aim was to evaluate the efficacy and safety of a new CO and 1540-nm laser-assisted blepharoplasty technique applied to the upper and lower eyelids. A total of 38 patients were enrolled.

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Background: Axillary bromhidrosis is an apocrine glands hyperactivity disease.

Methods: A total of 24 patients (15 men and 9 women) with axillary bromhidrosis underwent a laser procedure with a 1,444-nm Nd:YAG laser. Parameters evaluated in this study were as follows: the degree of malodor (T0, baseline; T30, after 1 month; and T180, after 6 months), postoperative pain, short-term decreased mobility (T1, after 1 day; T7, after 7 days; and T30, after 1 month), and overall satisfaction (T30, after 1 month and T180, after 6 months).

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Background: Lipoma is the most common benign mesenchymal tumor that is composed of mature fat cells. Subdermal laser lipoma treatment may be recommended as an alternative to surgery for its removal.

Purpose: The purpose of the study was to investigate the efficacy of the 1,444 nm Nd:YAG laser subcutaneous intralesional application as a treatment option for lipoma.

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Carbon peel laser treatment has been described for the improvement of skin texture, with pore reduction and acne lesion treatment. The technique consists of applying a carbon mask to the face for about ten minutes followed by laser irradiation with a Q-switched 1064 nm laser. This mechanism of action seems to be related to small carbon molecules binding both the corneocytes and serum within the hair follicles; the effect of the laser eliminates carbon bound to skin particles and the high temperature generated reduces sebum production by sebaceous glands and inhibits Cutibacterium acnes replication.

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Background: Acne is defined as a chronic inflammatory disease of the pilosebaceous units, mainly affecting the face of young adults, but the chest and back can be involved as well. Oral antibiotics, topical retinoids, azelaic acid, benzoyl peroxide, and isotretinoin represent the most common treatment used for the treatment of acne, but several adverse effects and a lack of durable remission, with poor adherence by the patients, have been reported thus far. Lasers have been shown to be effective and safe to treat acne; intense pulsed light (IPL) demonstrates high efficacy rates, minimal discomfort, rapid recovery times, and excellent cosmetic and therapeutic outcomes.

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