Publications by authors named "Pic A"

Objective: This study explored the lived experience of Delaware families residing in homeless shelters and motels with young children. We focused on their daily experiences to gain understanding about their day-to-day living to foster understanding about optimal supports that can facilitate more permanent housing arrangements.

Methods: We used qualitative approaches to obtain descriptions about the daily lives of families experiencing homelessness with young children.

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Date Of Birth: 29/07/1993; gender: female.

Pre-treatment Documents: 19 years 2 months old: 29/07/1993.

Diagnosis: Skeletal class II with mandibular laterognathia and retrusion, hypodivergent facial pattern; class II division 1, transverse maxillary deficiency with left unilateral posterior cross bite; missing teeth before treatment: 18 28 38 48.

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Background: The radial tuberosity contributes to the biceps supination moment arm and the elbow flexion moment. The purpose of our study was to compare the impact of a cortical bone trough versus an anatomic repair on measurements of the forearm supination moment arm and elbow flexion force efficiency. Our hypothesis was that a trough repair would decrease the tuberosity height, the native biceps supination moment arm, and elbow flexion force efficiency compared with an anatomic repair.

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Article Synopsis
  • The study aimed to analyze the clinical, biochemical, and genetic characteristics of Mediterranean patients with resistance to thyroid hormone (RTH) caused by mutations in the TRβ gene over a 15-year period.
  • A total of 166 blood samples were studied, leading to the identification of mutations in 50 patients, with a majority being women and an average diagnostic age of around 33 years.
  • The research revealed notable clinical features like goiter and hyperkinetic behavior, and found four new mutations in the TRβ gene, adding to existing knowledge on RTH characteristics in this population.
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In the yeast Saccharomyces cerevisiae, the MADS-box protein Mcm1, which is highly related to mammalian SRF (serum response factor), forms a ternary complex with SFF (Swi five factor) to regulate the cell cycle expression of genes such as SWI5, CLB2 and ACE2. Here we show that the forkhead protein Fkh2 is a component of SFF and is essential for ternary complex formation on the SWI5 and ACE2 promoters. Fkh2 is essential for the correct cell cycle periodicity of SWI5 and CLB2 gene expression and is phosphorylated with a timing that is consistent with a role in this expression.

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Several methods for adult height prediction are currently in use. All are subject to a wide range of error which is thought to result, at least in part, from the use of bone age estimation. Following the suggestion made by Karlberg to predict adult height of pubertal children by the use of the 'Infancy-Childhood-Puberty model' (ICP), growth data of 39 normal boys who were followed from infancy until adult height was attained were reviewed.

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Variations in the amplitude of the Q wave in lead CM5 during computerised exercise stress testing were studied in 220 patients and compared with the results of coronary angiography. The average amplitude of the Q wave increases during exercise in athletes (n = 30) from 3 +/- 2.75 mm to 4.

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Two hundred and fifteen patients were examined: 20 athletes, 40 subjects with radiologically normal coronary arteries (NCA) and 155 patients with one or more coronary artery stenoses (82 without, 73 with previous myocardial infarction). Exercise testing was by bicycle ergometry. The ECG recordings obtained by a computerised system had stable base lines and variations in QRS amplitude related to respiration were eliminated.

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100 inoperable coronary patients defined by severe angina, multistenosed vessels and narrowed or thrombosed distal beds performed a symptom-limited exercise test before coronary angiogram. During a 46 +/- 30 month period of follow-up 29 died, 25 of whom by cardiac cause. Among the exercise test data, the most discriminant for long-term survival was the exercise capacity, in spite of a poor correlation parameter for prediction of life expectancy.

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The action of dysopyramide was studied in 13 patients, 11 with ventricular and 2 with supraventricular arrhythmias. The drug was given parenterally at first and then by mouth. The patients were monitored with an arrhythmia counter and the plasma levels of disopyramide measured throughout the treatment period.

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