Publications by authors named "Piamkamon Vacharotayangul"

Objectives: The objective of this study was to characterize the current oral medicine (OM) workforce by examining the distribution of OM diplomates (OMDs) across the Unites States and to determine the need for expanding access to care.

Study Design: The OMD access was calculated based on the OMDs per 10,000 state population from the 2020 US Census data as well as their distance from state capitals and most populated cities. OMD penetrance in hospitals and cancer centers was assessed at National Cancer Care Network (NCCN) cancer centers, and Best Hospitals as reported in the 2022 US News and World Report (USNWR).

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Objectives: We aimed to assess the effectiveness of the use of topical imiquimod for the management of oral leukoplakia (OL).

Methods: This was a retrospective study. Medical chart reviews were conducted to identify patients with biopsy-proven OL treated with topical 5% imiquimod.

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Article Synopsis
  • - Proliferative verrucous leukoplakia (PVL) is a serious oral condition with a high chance of becoming invasive cancer, and there's currently no effective treatment. Recent findings point to a strong immune presence in PVL, leading researchers to explore immune checkpoint therapy as a potential treatment option.
  • - This study aimed to assess the safety and effectiveness of anti-PD-1 therapy (nivolumab) for treating high-risk PVL in a phase 2 clinical trial with 33 participants, monitored over about 21 months.
  • - Results showed that 36% of patients experienced a significant reduction in their condition, while some faced worsening disease; researchers also looked at immune responses and genetic factors as part of the treatment
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Oral dysesthesia (OD) is a diagnosis of exclusion that manifests as an unpleasant and abnormal sensation of the oral mucosa without any noticeable oral lesions. Burning sensation is one of the manifestations of OD which may advocate for similar pharmacotherapeutic options to burning mouth syndrome (BMS), resulting in possible adverse events. The aim of these case reports was to illustrate the significance and rationale for the use of oral devices as a mechanical/physical barrier and a safe approach in the management of OD, without experiencing any antagonistic effects from pharmacotherapeutic agents.

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Immune checkpoint inhibitors (ICIs) are a revolutionary class of antineoplastic therapy that restore anti-tumor immunity. Consequences of this enhanced immune response include a multitude of immune related adverse events (irAEs) that can affect any body system, including the mouth. Orofacial irAEs reproduce features of numerous immune-mediated conditions, including oral lichen planus, mucous membrane pemphigoid, and Sjögren syndrome, among others.

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Objective: To compare the reported efficacy and costs of available interventions used for the management of oral lichen planus (OLP).

Materials And Methods: A systematic literature search was performed from database inception until March 2021 in MEDLINE via PubMed and the Cochrane library following PRISMA guidelines. Only randomized controlled trials (RCT) comparing an active intervention with placebo or different active interventions for OLP management were considered.

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Article Synopsis
  • Immunotherapy with immune checkpoint inhibitors (ICIs) has significantly improved survival rates for many advanced cancers but can lead to immune-related adverse events (irAEs), affecting any organ system.
  • This review focuses on the less-studied oral manifestations of irAEs, detailing mucosal and salivary gland toxicities, and recommends a grading system along with management strategies.
  • Oral healthcare providers play a crucial role in recognizing and managing these oral irAEs alongside oncologists, as they can vary from mild symptoms to severe, life-threatening conditions.
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Background: Effects of various Highly Active Antiretroviral Therapy (HAART) regimens on oral heath are unclear. Objectives: We aimed to evaluate effects of HAART on oral manifestations, salivary flow rates (SFR) and Candida species in HIV-infected patients who took mostly non-protease inhibitor-based HAART regimens.

Material And Methods: A cross-sectional study was performed on HIV-infected patients taking and never taken HAART who attended Thai Red Cross AIDS Research Centre (n = 48).

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Dry mouth is common in elderly patients. However, the use of saliva substitute has been limited due to its inedibility. This study investigated the efficacy of oral moisturizing jelly (OMJ), a novel edible saliva substitute.

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Objective: This study was designed to investigate the prevalence of oral human papillomavirus (HPV) infection among HIV-positive and HIV-negative Thai men and women.

Methods: Participants including men who have sex with men (MSM) and heterosexual women were enrolled at the Thai Red Cross Anonymous Clinic in Bangkok. History taking and oral examination were performed by three independent dentists after calibration.

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To investigate the knowledge and attitudes of Thai dental practitioners regarding patients with HIV, a cross-sectional study using self-administered questionnaires was conducted. The questionnaires requested demographic information and included questions evaluating the knowledge and attitude of dental practitioners towards HIV. The results were analyzed using Scheffe method for multiple comparisons at the 95 percent confidence level.

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Despite the advancement in highly active antiretroviral therapy and improved health status of HIV-infected individuals, dental problems are still affecting their life and well-beings. We aimed to establish the prevalence of oral and dental complaints among HIV-infected patients, the prevalence of delayed access to dental service, and factors related with delayed access to dental service. A cross-sectional study using self-report questionnaire completed by the HIV-positive subjects was conducted at the largest HIV research clinic in Thailand during 2009-2010.

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