[Efficacy of internet-based interventions for depression available in Germany-A systematic review and meta-analysis].

Background: Internet-based interventions (IBIs) for the treatment of depression have been found to have positive effects in international meta-analyses; however, it is unclear whether these effects also extend to IBIs specifically available in Germany. The aim of this meta-analysis was to estimate the immediate effects and the long-term effects of IBIs available in Germany free of charge or available on prescription and covered by the public health insurances as so-called digital health applications (DiGAs) and to compare the efficacy of DiGAs and freely available IBIs.

Method: A systematic literature search and random-effects meta-analysis were performed (preregistration: INPLASY202250070).